Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GUCY1A2
  • Mouse genes Gucy1a2
  • Rat genes Gucy1a2
  • Zfish genes gucy1a2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gucy1a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004383	guanylate cyclase activity	Gucy1a2	IDA		Rat	PMID:11121588|RGD:632921
Molecular Function	GO:0005515	protein binding	GUCY1A2	IPI	UniProtKB:Q14160	Human	PMID:24550280
Molecular Function	GO:0005515	protein binding	GUCY1A2	IPI	UniProtKB:Q12959	Human	PMID:30126976
Molecular Function	GO:0005515	protein binding	GUCY1A2	IPI	UniProtKB:Q14160	Human	PMID:30126976
Molecular Function	GO:0005515	protein binding	GUCY1A2	IPI	UniProtKB:O15499	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Gucy1a2	IPI	UniProtKB:P31016	Rat	PMID:11572861|RGD:70590
Molecular Function	GO:0005515	protein binding	Gucy1a2	IPI	UniProtKB:Q62108	Rat	PMID:17950729|RGD:2324997
Molecular Function	GO:0044877	protein-containing complex binding	Gucy1a2	IPI	RGD:68436	Rat	PMID:9294115|RGD:14696711
Biological Process	GO:0007263	nitric oxide mediated signal transduction	Gucy1a2	IMP	MGI:MGI:3640794	Mouse	PMID:16614755
Biological Process	GO:0010750	positive regulation of nitric oxide mediated signal transduction	Gucy1a2	IMP	MGI:MGI:3640794	Mouse	PMID:16614755

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern