Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GUCA2B
  • Mouse genes Guca2b
  • Rat genes Guca2b
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Guca2b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	GUCA2B	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GUCA2B	IPI	UniProtKB:Q9UMX0	Human	PMID:32296183
Cellular Component	GO:0070062	extracellular exosome	GUCA2B	HDA		Human	PMID:23533145
Cellular Component	GO:0001750	photoreceptor outer segment	Guca2b	IDA		Mouse	PMID:22183407
Biological Process	GO:0060612	adipose tissue development	Guca2b	IMP	MGI:MGI:2679505	Mouse	PMID:24898144
Biological Process	GO:0007589	body fluid secretion	Guca2b	IMP	MGI:MGI:2679505	Mouse	PMID:14561709
Biological Process	GO:0019934	cGMP-mediated signaling	Guca2b	IDA		Rat	PMID:9094754|RGD:731150
Biological Process	GO:0097009	energy homeostasis	Guca2b	IMP	MGI:MGI:2679505	Mouse	PMID:24898144
Biological Process	GO:0042593	glucose homeostasis	Guca2b	IMP	MGI:MGI:2679505	Mouse	PMID:24898144
Biological Process	GO:0035264	multicellular organism growth	Guca2b	IMP	MGI:MGI:2679505	Mouse	PMID:24898144
Biological Process	GO:0045776	negative regulation of blood pressure	Guca2b	IMP	MGI:MGI:2679505	Mouse	PMID:14561709
Biological Process	GO:0002023	reduction of food intake in response to dietary excess	Guca2b	IMP	MGI:MGI:2679505	Mouse	PMID:24898144
Biological Process	GO:0070294	renal sodium ion absorption	Guca2b	IMP	MGI:MGI:2679505	Mouse	PMID:14561709
Biological Process	GO:0009749	response to glucose	Guca2b	IMP	MGI:MGI:2679505	Mouse	PMID:24898144

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern