Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GSTK1
  • Mouse genes Gstk1
  • Rat genes Gstk1
  • Zfish genes gstk1,gstk2,gstk4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gstk1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004602	glutathione peroxidase activity	GSTK1	IDA		Human	PMID:14742434
Molecular Function	GO:0004602	glutathione peroxidase activity	Gstk1	IDA		Mouse	PMID:12720545
Molecular Function	GO:0004364	glutathione transferase activity	GSTK1	IDA		Human	PMID:14742434
Molecular Function	GO:0004364	glutathione transferase activity	Gstk1	IDA		Mouse	PMID:12720545
Molecular Function	GO:0005515	protein binding	GSTK1	IPI	UniProtKB:Q60994	Human	PMID:19011089
Molecular Function	GO:0005515	protein binding	GSTK1	IPI	UniProtKB:Q60994	Human	PMID:22583869
Molecular Function	GO:0005515	protein binding	GSTK1	IPI	UniProtKB:O95273	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GSTK1	IPI	UniProtKB:Q8IZU0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GSTK1	IPI	UniProtKB:Q8IZU0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Gstk1	IPI	UniProtKB:Q60994	Mouse	MGI:MGI:3820756|PMID:19011089
Cellular Component	GO:0070062	extracellular exosome	GSTK1	HDA		Human	PMID:19199708
Cellular Component	GO:0016020	membrane	GSTK1	HDA		Human	PMID:19946888
Cellular Component	GO:0005743	mitochondrial inner membrane	Gstk1	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005759	mitochondrial matrix	Gstk1	IDA		Rat	PMID:14561759|RGD:1580664
Cellular Component	GO:0005739	mitochondrion	Gstk1	IDA		Mouse	PMID:12720545
Cellular Component	GO:0005739	mitochondrion	Gstk1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Gstk1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005777	peroxisome	GSTK1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005777	peroxisome	GSTK1	IDA		Human	PMID:14742434
Biological Process	GO:0030855	epithelial cell differentiation	GSTK1	IEP		Human	PMID:21492153
Biological Process	GO:0006749	glutathione metabolic process	Gstk1	IDA		Mouse	PMID:12720545

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern