Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GSTA1,GSTA2,GSTA3,GSTA5
  • Mouse genes Gsta2
  • Rat genes Gsta1,Gsta2,Gsta5
  • Zfish genes gsta.1,gsta.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gsta2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035731	dinitrosyl-iron complex binding	Gsta1	IDA		Rat	PMID:17197701|RGD:1641938
Molecular Function	GO:0035731	dinitrosyl-iron complex binding	Gsta2	IPI	CHEBI:64609	Rat	PMID:17197701|RGD:1641938
Molecular Function	GO:0005504	fatty acid binding	GSTA1	IPI	CHEBI:72639	Human	PMID:16624487
Molecular Function	GO:0043295	glutathione binding	Gsta5	IDA		Rat	PMID:17112229|RGD:12793043
Molecular Function	GO:0043295	glutathione binding	Gsta1	IDA		Rat	PMID:17112229|RGD:12793043
Molecular Function	GO:0043295	glutathione binding	Gsta2	IDA		Rat	PMID:10751412|RGD:12793023
Molecular Function	GO:0043295	glutathione binding	Gsta2	IDA		Rat	PMID:15152091|RGD:12793030
Molecular Function	GO:0043295	glutathione binding	Gsta2	IDA		Rat	PMID:17112229|RGD:12793043
Molecular Function	GO:0004602	glutathione peroxidase activity	GSTA1	IDA		Human	PMID:16624487
Molecular Function	GO:0004364	glutathione transferase activity	GSTA1	IDA		Human	PMID:11851347
Molecular Function	GO:0004364	glutathione transferase activity	GSTA1	IDA		Human	PMID:20606271
Molecular Function	GO:0004364	glutathione transferase activity	GSTA1	IDA		Human	PMID:9084911
Molecular Function	GO:0004364	glutathione transferase activity	Gsta2	IDA		Mouse	MGI:MGI:1203931|PMID:9606968
Molecular Function	GO:0004364	glutathione transferase activity	Gsta5	IDA		Rat	PMID:17112229|RGD:12793043
Molecular Function	GO:0004364	glutathione transferase activity	Gsta1	IDA		Rat	PMID:17112229|RGD:12793043
Molecular Function	GO:0004364	glutathione transferase activity	Gsta2	IDA		Rat	PMID:10751412|RGD:12793023
Molecular Function	GO:0004364	glutathione transferase activity	Gsta2	IDA		Rat	PMID:15152091|RGD:12793030
Molecular Function	GO:0004364	glutathione transferase activity	Gsta2	IDA		Rat	PMID:17112229|RGD:12793043
Molecular Function	GO:0004364	glutathione transferase activity	gsta.2	IDA		Zfish	PMID:25461745
Molecular Function	GO:0005515	protein binding	GSTA2	IPI	UniProtKB:O15217	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GSTA2	IPI	UniProtKB:O15217	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	GSTA2	IPI	UniProtKB:O15217	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GSTA2	IPI	UniProtKB:Q7RTV2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GSTA2	IPI	UniProtKB:O15217	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GSTA2	IPI	UniProtKB:O15217	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GSTA2	IPI	UniProtKB:Q7RTV2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GSTA5	IPI	UniProtKB:P09210	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GSTA5	IPI	UniProtKB:P09210	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GSTA5	IPI	UniProtKB:Q8N6V9	Human	PMID:32296183
Molecular Function	GO:0042803	protein homodimerization activity	Gsta2	IDA		Rat	PMID:15152091|RGD:12793030
Molecular Function	GO:0004769	steroid delta-isomerase activity	GSTA1	IDA		Human	PMID:11152686
Cellular Component	GO:0005829	cytosol	GSTA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	GSTA2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	GSTA3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	GSTA5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Gsta5	IDA		Rat	PMID:17112229|RGD:12793043
Cellular Component	GO:0005829	cytosol	Gsta1	IDA		Rat	PMID:17112229|RGD:12793043
Cellular Component	GO:0005829	cytosol	Gsta1	IDA		Rat	PMID:17197701|RGD:1641938
Cellular Component	GO:0005829	cytosol	Gsta2	IDA		Rat	PMID:17112229|RGD:12793043
Cellular Component	GO:0005829	cytosol	Gsta2	IDA		Rat	PMID:17197701|RGD:1641938
Cellular Component	GO:0070062	extracellular exosome	GSTA1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	GSTA1	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	GSTA2	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	GSTA3	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	GSTA5	HDA		Human	PMID:23533145
Cellular Component	GO:0031090	organelle membrane	Gsta1	IDA		Rat	PMID:17197701|RGD:1641938
Biological Process	GO:0007568	aging	Gsta1	IEP		Rat	PMID:15967433|RGD:2306661
Biological Process	GO:0007568	aging	Gsta2	IEP		Rat	PMID:15967433|RGD:2306661
Biological Process	GO:0030855	epithelial cell differentiation	GSTA1	IEP		Human	PMID:21492153
Biological Process	GO:0030855	epithelial cell differentiation	GSTA2	IEP		Human	PMID:21492153
Biological Process	GO:1901687	glutathione derivative biosynthetic process	GSTA1	IDA		Human	PMID:9084911
Biological Process	GO:0006749	glutathione metabolic process	GSTA1	IDA		Human	PMID:11851347
Biological Process	GO:0006749	glutathione metabolic process	GSTA1	IDA		Human	PMID:20606271
Biological Process	GO:0043651	linoleic acid metabolic process	GSTA1	IDA		Human	PMID:16624487
Biological Process	GO:0006693	prostaglandin metabolic process	GSTA1	IDA		Human	PMID:9084911
Biological Process	GO:0009617	response to bacterium	Gsta2	IEP		Mouse	PMID:23012479
Biological Process	GO:0031667	response to nutrient levels	Gsta1	IEP		Rat	PMID:19191009|RGD:2316562
Biological Process	GO:0035634	response to stilbenoid	Gsta2	IEP		Mouse	MGI:MGI:4943399|PMID:17086191
Biological Process	GO:0042178	xenobiotic catabolic process	Gsta5	IDA		Rat	PMID:17112229|RGD:12793043
Biological Process	GO:0042178	xenobiotic catabolic process	Gsta1	IDA		Rat	PMID:17112229|RGD:12793043
Biological Process	GO:0042178	xenobiotic catabolic process	Gsta2	IDA		Rat	PMID:17112229|RGD:12793043

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern