Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GRAMD1A
  • Mouse genes Gramd1a
  • Rat genes Gramd1a
  • Zfish genes gramd1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gramd1a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015485	cholesterol binding	Gramd1a	IDA		Mouse	MGI:MGI:6242147|PMID:30220461
Molecular Function	GO:0120020	cholesterol transfer activity	Gramd1a	IMP		Mouse	MGI:MGI:6242147|PMID:30220461
Molecular Function	GO:0005515	protein binding	GRAMD1A	IPI	UniProtKB:Q53SE7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GRAMD1A	IPI	UniProtKB:P21145	Human	PMID:32296183
Cellular Component	GO:0005829	cytosol	GRAMD1A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	GRAMD1A	IDA		Human	PMID:29469807
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Gramd1a	IDA		Mouse	MGI:MGI:6242147|PMID:30220461
Cellular Component	GO:0140268	endoplasmic reticulum-plasma membrane contact site	Gramd1a	IDA		Mouse	MGI:MGI:6242147|PMID:30220461
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	GRAMD1A	IDA		Human	PMID:29469807
Cellular Component	GO:0044232	organelle membrane contact site	GRAMD1A	IDA		Human	PMID:29469807
Cellular Component	GO:0005886	plasma membrane	GRAMD1A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Gramd1a	IDA		Mouse	MGI:MGI:6242147|PMID:30220461
Biological Process	GO:0071397	cellular response to cholesterol	Gramd1a	IDA		Mouse	MGI:MGI:6242147|PMID:30220461

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern