Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPX2
  • Mouse genes Gpx2
  • Rat genes Gpx2
  • Zfish genes gpx2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpx2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004602	glutathione peroxidase activity	Gpx2	IMP	MGI:MGI:1888703	Mouse	PMID:11518697
Molecular Function	GO:0004602	glutathione peroxidase activity	Gpx2	IMP	MGI:MGI:1888703	Mouse	PMID:12751789
Molecular Function	GO:0004602	glutathione peroxidase activity	Gpx2	IDA		Rat	PMID:9685647|RGD:1299548
Biological Process	GO:0051702	biological process involved in interaction with symbiont	Gpx2	IGI	MGI:MGI:104887	Mouse	PMID:12751789
Biological Process	GO:0051702	biological process involved in interaction with symbiont	Gpx2	IGI	MGI:MGI:106609	Mouse	PMID:12751789
Biological Process	GO:0098869	cellular oxidant detoxification	Gpx2	IMP	MGI:MGI:1888703	Mouse	MGI:MGI:2150247|PMID:11518697
Biological Process	GO:0002862	negative regulation of inflammatory response to antigenic stimulus	Gpx2	IGI	MGI:MGI:106609	Mouse	PMID:12751789
Biological Process	GO:0002862	negative regulation of inflammatory response to antigenic stimulus	Gpx2	IGI	MGI:MGI:104887	Mouse	PMID:12751789
Biological Process	GO:0009751	response to salicylic acid	Gpx2	IEP		Rat	PMID:16038882|RGD:152998891
Biological Process	GO:0010269	response to selenium ion	Gpx2	IEP		Rat	PMID:23271678|RGD:152998882
Biological Process	GO:0009609	response to symbiotic bacterium	Gpx2	IGI	MGI:MGI:104887	Mouse	PMID:12751789
Biological Process	GO:0009609	response to symbiotic bacterium	Gpx2	IGI	MGI:MGI:106609	Mouse	PMID:12751789
Biological Process	GO:0001659	temperature homeostasis	Gpx2	IGI	MGI:MGI:104887	Mouse	PMID:11518697
Biological Process	GO:0001659	temperature homeostasis	Gpx2	IGI	MGI:MGI:106609	Mouse	PMID:11518697

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern