Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPR68
  • Mouse genes Gpr68
  • Rat genes Gpr68
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpr68

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Biological Process	GO:0071467	cellular response to pH	Gpr68	IMP	MGI:MGI:5445001	Mouse	PMID:22733973
Biological Process	GO:0030073	insulin secretion	Gpr68	IMP	MGI:MGI:5445001	Mouse	PMID:22733973
Biological Process	GO:0030224	monocyte differentiation	Gpr68	IMP	MGI:MGI:3849457	Mouse	PMID:19479052
Biological Process	GO:0045656	negative regulation of monocyte differentiation	Gpr68	IMP	MGI:MGI:3849457	Mouse	PMID:19479052
Biological Process	GO:0036035	osteoclast development	Gpr68	IMP	MGI:MGI:3849457	Mouse	PMID:19479052
Biological Process	GO:0032024	positive regulation of insulin secretion	Gpr68	IMP	MGI:MGI:5445001	Mouse	PMID:22733973
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Gpr68	IMP	MGI:MGI:5445001	Mouse	PMID:22733973
Biological Process	GO:2001206	positive regulation of osteoclast development	Gpr68	IMP	MGI:MGI:3849457	Mouse	PMID:19479052

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern