Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPIHBP1
  • Mouse genes Gpihbp1
  • Rat genes Gpihbp1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpihbp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035478	chylomicron binding	GPIHBP1	IDA		Human	PMID:19304573
Molecular Function	GO:0035478	chylomicron binding	Gpihbp1	IMP		Mouse	MGI:MGI:3770110|PMID:17403372
Molecular Function	GO:0008035	high-density lipoprotein particle binding	Gpihbp1	IDA		Mouse	PMID:12496272
Molecular Function	GO:0035473	lipase binding	GPIHBP1	IPI	UniProtKB:P06858	Human	PMID:20124439
Molecular Function	GO:0035473	lipase binding	GPIHBP1	IPI	UniProtKB:P11151	Human	PMID:29899144
Molecular Function	GO:0035473	lipase binding	Gpihbp1	IPI	UniProtKB:Q29524	Mouse	MGI:MGI:3770110|PMID:17403372
Molecular Function	GO:0060230	lipoprotein lipase activator activity	GPIHBP1	IDA		Human	PMID:29899144
Molecular Function	GO:0071813	lipoprotein particle binding	GPIHBP1	IDA		Human	PMID:17997385
Molecular Function	GO:0071813	lipoprotein particle binding	Gpihbp1	IMP		Mouse	MGI:MGI:3770110|PMID:17403372
Molecular Function	GO:0005515	protein binding	GPIHBP1	IPI	UniProtKB:P06858	Human	PMID:20124439
Molecular Function	GO:0005515	protein binding	GPIHBP1	IPI	UniProtKB:P06858	Human	PMID:30559189
Molecular Function	GO:0005515	protein binding	GPIHBP1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0140318	protein transporter activity	Gpihbp1	IDA		Mouse	MGI:MGI:4820887|PMID:20620994
Cellular Component	GO:0016324	apical plasma membrane	Gpihbp1	IDA		Mouse	MGI:MGI:4820887|PMID:20620994
Cellular Component	GO:0016323	basolateral plasma membrane	Gpihbp1	IDA		Mouse	MGI:MGI:4820887|PMID:20620994
Cellular Component	GO:1902494	catalytic complex	GPIHBP1	IPI		Human	PMID:30559189
Cellular Component	GO:0009986	cell surface	Gpihbp1	IDA		Mouse	PMID:12496272
Cellular Component	GO:0009897	external side of plasma membrane	GPIHBP1	IDA		Human	PMID:17997385
Cellular Component	GO:0009897	external side of plasma membrane	GPIHBP1	IDA		Human	PMID:20124439
Cellular Component	GO:0009897	external side of plasma membrane	Gpihbp1	IDA		Mouse	MGI:MGI:3770110|PMID:17403372
Cellular Component	GO:0009897	external side of plasma membrane	Gpihbp1	IDA		Mouse	MGI:MGI:4820887|PMID:20620994
Cellular Component	GO:0005886	plasma membrane	Gpihbp1	IDA		Mouse	PMID:12496272
Biological Process	GO:0042632	cholesterol homeostasis	Gpihbp1	IMP		Mouse	MGI:MGI:3770110|PMID:17403372
Biological Process	GO:0006886	intracellular protein transport	Gpihbp1	IDA		Mouse	MGI:MGI:4820887|PMID:20620994
Biological Process	GO:0006869	lipid transport	Gpihbp1	IDA		Mouse	PMID:12496272
Biological Process	GO:0090321	positive regulation of chylomicron remnant clearance	Gpihbp1	IMP		Mouse	MGI:MGI:3770110|PMID:17403372
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	GPIHBP1	IMP		Human	PMID:20124439
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	GPIHBP1	IDA		Human	PMID:29899144
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	Gpihbp1	IMP		Mouse	MGI:MGI:3770110|PMID:17403372
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	Gpihbp1	IDA		Mouse	MGI:MGI:4412214|PMID:19542565
Biological Process	GO:0017038	protein import	Gpihbp1	IDA		Mouse	MGI:MGI:4820887|PMID:20620994
Biological Process	GO:0034394	protein localization to cell surface	Gpihbp1	IDA		Mouse	MGI:MGI:4820887|PMID:20620994
Biological Process	GO:0050821	protein stabilization	GPIHBP1	IDA		Human	PMID:29899144
Biological Process	GO:0050821	protein stabilization	Gpihbp1	IDA		Mouse	MGI:MGI:4412214|PMID:19542565
Biological Process	GO:0071503	response to heparin	GPIHBP1	IMP		Human	PMID:20124439
Biological Process	GO:0045056	transcytosis	Gpihbp1	IDA		Mouse	MGI:MGI:4820887|PMID:20620994
Biological Process	GO:0019433	triglyceride catabolic process	GPIHBP1	IDA		Human	PMID:30559189
Biological Process	GO:0070328	triglyceride homeostasis	GPIHBP1	IMP		Human	PMID:20124439
Biological Process	GO:0070328	triglyceride homeostasis	Gpihbp1	IMP		Mouse	MGI:MGI:3770110|PMID:17403372
Biological Process	GO:0070328	triglyceride homeostasis	Gpihbp1	IGI	UniProtKB:Q9Z1P8	Mouse	MGI:MGI:4412214|PMID:19542565

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern