Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPD1
  • Mouse genes Gpd1
  • Rat genes Gpd1
  • Zfish genes gpd1a,gpd1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004368	glycerol-3-phosphate dehydrogenase (quinone) activity	Gpd1	IDA		Rat	PMID:1834654|RGD:1599371
Molecular Function	GO:0047952	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	Gpd1	IDA		Mouse	PMID:11147825
Molecular Function	GO:0047952	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	Gpd1	IDA		Mouse	PMID:6105153
Molecular Function	GO:0047952	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	Gpd1	IDA		Rat	PMID:12351438|RGD:2303499
Molecular Function	GO:0047952	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	Gpd1	IDA		Rat	PMID:9550546|RGD:1641824
Molecular Function	GO:0051287	NAD binding	Gpd1	IDA		Rat	PMID:9550546|RGD:1641824
Molecular Function	GO:0005515	protein binding	GPD1	IPI	UniProtKB:B3EWG5	Human	PMID:32296183
Cellular Component	GO:0005829	cytosol	Gpd1	IDA		Rat	PMID:1834654|RGD:1599371
Cellular Component	GO:0070062	extracellular exosome	GPD1	HDA		Human	PMID:19056867
Cellular Component	GO:0005739	mitochondrion	Gpd1	HDA		Mouse	PMID:18614015
Biological Process	GO:0005975	carbohydrate metabolic process	Gpd1	IDA		Rat	PMID:1834654|RGD:1599371
Biological Process	GO:0071320	cellular response to cAMP	Gpd1	IDA		Mouse	PMID:3027100
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Gpd1	IDA		Mouse	PMID:3027100
Biological Process	GO:0006094	gluconeogenesis	Gpd1	IMP		Mouse	PMID:12093800
Biological Process	GO:0006072	glycerol-3-phosphate metabolic process	Gpd1	IMP		Mouse	PMID:12093800
Biological Process	GO:0006072	glycerol-3-phosphate metabolic process	Gpd1	IDA		Rat	PMID:12351438|RGD:2303499
Biological Process	GO:0046486	glycerolipid metabolic process	Gpd1	IDA		Rat	PMID:2997397|RGD:1641825
Biological Process	GO:0006127	glycerophosphate shuttle	Gpd1	IMP	MGI:MGI:3692960	Mouse	PMID:11147825
Biological Process	GO:0006734	NADH metabolic process	Gpd1	IDA		Rat	PMID:12351438|RGD:2303499
Biological Process	GO:0006116	NADH oxidation	Gpd1	IMP	MGI:MGI:3692960	Mouse	PMID:11147825
Biological Process	GO:0006116	NADH oxidation	Gpd1	IDA		Rat	PMID:9550546|RGD:1641824
Biological Process	GO:0045821	positive regulation of glycolytic process	Gpd1	IMP	MGI:MGI:3692960	Mouse	PMID:11147825

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern