Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPC1
  • Mouse genes Gpc1
  • Rat genes Gpc1
  • Zfish genes gpc1a,gpc1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070052	collagen V binding	Gpc1	IPI	RGD:70922	Rat	PMID:15383532|RGD:5683638
Molecular Function	GO:0005507	copper ion binding	GPC1	IDA		Human	PMID:12732622
Molecular Function	GO:0017134	fibroblast growth factor binding	Gpc1	IDA		Mouse	MGI:MGI:4461098|PMID:20100867
Molecular Function	GO:0043236	laminin binding	Gpc1	IDA		Mouse	MGI:MGI:4461098|PMID:20100867
Molecular Function	GO:0005515	protein binding	GPC1	IPI	UniProtKB:Q6PRD1	Human	PMID:30282023
Molecular Function	GO:0005515	protein binding	GPC1	IPI	UniProtKB:Q8C419	Human	PMID:30282023
Molecular Function	GO:0005515	protein binding	Gpc1	IPI	UniProtKB:O94813	Rat	PMID:11375980|RGD:8554728
Cellular Component	GO:0062023	collagen-containing extracellular matrix	GPC1	HDA		Human	PMID:27559042
Cellular Component	GO:0005829	cytosol	GPC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	GPC1	HDA		Human	PMID:19199708
Cellular Component	GO:0031012	extracellular matrix	Gpc1	IDA		Mouse	MGI:MGI:4461098|PMID:20100867
Cellular Component	GO:0005576	extracellular region	GPC1	HDA		Human	PMID:27068509
Cellular Component	GO:0045121	membrane raft	GPC1	IDA		Human	PMID:12732622
Cellular Component	GO:0045121	membrane raft	Gpc1	IDA		Mouse	MGI:MGI:4461098|PMID:20100867
Cellular Component	GO:0043025	neuronal cell body	Gpc1	IDA		Rat	PMID:8207484|RGD:728605
Cellular Component	GO:0005654	nucleoplasm	GPC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	GPC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045202	synapse	Gpc1	EXP		Mouse	PMID:16452087
Cellular Component	GO:0045202	synapse	Gpc1	IDA		Mouse	PMID:16452087
Biological Process	GO:0061009	common bile duct development	gpc1a	IMP	ZFIN:ZDB-MRPHLNO-130516-5	Zfish	PMID:23336978
Biological Process	GO:0030200	heparan sulfate proteoglycan catabolic process	GPC1	IDA		Human	PMID:12732622
Biological Process	GO:0035622	intrahepatic bile duct development	gpc1a	IMP	ZFIN:ZDB-MRPHLNO-130516-5	Zfish	PMID:23336978
Biological Process	GO:0032288	myelin assembly	Gpc1	IDA		Rat	PMID:16407548|RGD:8553537
Biological Process	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	Gpc1	IDA		Mouse	MGI:MGI:4461098|PMID:20100867
Biological Process	GO:2001016	positive regulation of skeletal muscle cell differentiation	Gpc1	IEP		Mouse	MGI:MGI:4461098|PMID:20100867
Biological Process	GO:0014037	Schwann cell differentiation	Gpc1	IDA		Rat	PMID:16407548|RGD:8553537

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern