Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPAT4
  • Mouse genes Gpat4
  • Rat genes Gpat4
  • Zfish genes gpat4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpat4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004366	glycerol-3-phosphate O-acyltransferase activity	GPAT4	IDA		Human	PMID:18238778
Molecular Function	GO:0004366	glycerol-3-phosphate O-acyltransferase activity	Gpat4	IMP		Mouse	MGI:MGI:3793393|PMID:18238778
Molecular Function	GO:0005515	protein binding	Gpat4	IPI	UniProtKB:Q9Z2E9	Mouse	PMID:27806294
Cellular Component	GO:0005783	endoplasmic reticulum	GPAT4	IDA		Human	PMID:18238778
Cellular Component	GO:0005783	endoplasmic reticulum	Gpat4	IDA		Mouse	PMID:16449762
Cellular Component	GO:0016020	membrane	GPAT4	IDA		Human	PMID:18238778
Cellular Component	GO:0016020	membrane	GPAT4	HDA		Human	PMID:19946888
Biological Process	GO:0006637	acyl-CoA metabolic process	GPAT4	IDA		Human	PMID:18238778
Biological Process	GO:0046339	diacylglycerol metabolic process	Gpat4	IMP	MGI:MGI:3624276	Mouse	PMID:16449762
Biological Process	GO:0046339	diacylglycerol metabolic process	Gpat4	IMP	MGI:MGI:3624276	Mouse	PMID:16436371
Biological Process	GO:0006631	fatty acid metabolic process	Gpat4	IMP	MGI:MGI:3624276	Mouse	PMID:16436371
Biological Process	GO:0002071	glandular epithelial cell maturation	Gpat4	IMP	MGI:MGI:3624276	Mouse	PMID:16449762
Biological Process	GO:0007595	lactation	Gpat4	IMP	MGI:MGI:3624276	Mouse	PMID:16449762
Biological Process	GO:0008610	lipid biosynthetic process	Gpat4	IMP		Mouse	MGI:MGI:3623167|PMID:16449762
Biological Process	GO:0030879	mammary gland development	Gpat4	IMP	MGI:MGI:3624276	Mouse	PMID:16449762
Biological Process	GO:0006656	phosphatidylcholine biosynthetic process	GPAT4	IDA		Human	PMID:18238778
Biological Process	GO:0040014	regulation of multicellular organism growth	Gpat4	IMP	MGI:MGI:3624276	Mouse	PMID:16436371
Biological Process	GO:0019432	triglyceride biosynthetic process	Gpat4	IMP		Mouse	MGI:MGI:3623703|PMID:16436371
Biological Process	GO:0006641	triglyceride metabolic process	Gpat4	IMP	MGI:MGI:3624276	Mouse	PMID:16449762
Biological Process	GO:0006641	triglyceride metabolic process	Gpat4	IMP	MGI:MGI:3624276	Mouse	PMID:16436371

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern