Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GNAL
  • Mouse genes Gnal
  • Rat genes Gnal
  • Zfish genes gnal
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gnal

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	GNAL	IPI	UniProtKB:Q5SSG4	Human	PMID:23994616
Cellular Component	GO:0070062	extracellular exosome	GNAL	HDA		Human	PMID:23533145
Biological Process	GO:0007190	activation of adenylate cyclase activity	Gnal	IDA		Mouse	PMID:12488442
Biological Process	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	Gnal	IGI	MGI:MGI:99578	Mouse	PMID:17194762
Biological Process	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	Gnal	IGI	MGI:MGI:95777	Mouse	PMID:17194762
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Gnal	IDA		Mouse	PMID:2499043
Biological Process	GO:1903351	cellular response to dopamine	Gnal	IMP		Rat	PMID:31678405|RGD:150429833
Biological Process	GO:1900452	regulation of long-term synaptic depression	Gnal	IMP		Rat	PMID:31678405|RGD:150429833
Biological Process	GO:0001975	response to amphetamine	Gnal	IMP	MGI:MGI:2151207	Mouse	PMID:11404425
Biological Process	GO:0031000	response to caffeine	Gnal	IMP	MGI:MGI:2151207	Mouse	PMID:11404425
Biological Process	GO:0007608	sensory perception of smell	Gnal	IMP	MGI:MGI:2151207	Mouse	PMID:9459443

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern