Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GM2A
  • Mouse genes Gm2a
  • Rat genes Gm2a
  • Zfish genes gm2a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gm2a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032428	beta-N-acetylgalactosaminidase activity	Gm2a	IDA		Rat	PMID:9770472|RGD:1598995
Molecular Function	GO:0004563	beta-N-acetylhexosaminidase activity	Gm2a	IMP	MGI:MGI:1861930	Mouse	PMID:9584189
Molecular Function	GO:0008047	enzyme activator activity	Gm2a	IDA		Mouse	PMID:7980537
Molecular Function	GO:0005319	lipid transporter activity	Gm2a	IDA		Rat	PMID:8948454|RGD:1598996
Molecular Function	GO:0016004	phospholipase activator activity	Gm2a	IDA		Rat	PMID:9770472|RGD:1598995
Cellular Component	GO:0016324	apical plasma membrane	Gm2a	IDA		Rat	PMID:10073593|RGD:1598994
Cellular Component	GO:0016323	basolateral plasma membrane	Gm2a	IDA		Rat	PMID:10073593|RGD:1598994
Cellular Component	GO:0005737	cytoplasm	Gm2a	IDA		Rat	PMID:10073593|RGD:1598994
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	Gm2a	IDA		Rat	PMID:10073593|RGD:1598994
Cellular Component	GO:0005829	cytosol	GM2A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	GM2A	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	GM2A	HDA		Human	PMID:23533145
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	GM2A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005764	lysosome	Gm2a	IDA		Rat	PMID:8948454|RGD:1598996
Cellular Component	GO:0005739	mitochondrion	Gm2a	HDA		Mouse	PMID:14651853
Biological Process	GO:0006689	ganglioside catabolic process	Gm2a	IMP	MGI:MGI:1861930	Mouse	PMID:9223328
Biological Process	GO:0001573	ganglioside metabolic process	Gm2a	IDA		Rat	PMID:9770472|RGD:1598995
Biological Process	GO:0007611	learning or memory	Gm2a	IMP	MGI:MGI:1861930	Mouse	PMID:9223328
Biological Process	GO:0019915	lipid storage	Gm2a	IMP	MGI:MGI:1861930	Mouse	PMID:9223328
Biological Process	GO:0006869	lipid transport	Gm2a	IDA		Rat	PMID:8948454|RGD:1598996
Biological Process	GO:0051651	maintenance of location in cell	Gm2a	IMP	MGI:MGI:1861930	Mouse	PMID:9223328
Biological Process	GO:0050877	nervous system process	Gm2a	IMP	MGI:MGI:1861930	Mouse	PMID:9223328
Biological Process	GO:0050885	neuromuscular process controlling balance	Gm2a	IMP	MGI:MGI:1861930	Mouse	PMID:9223328
Biological Process	GO:0009313	oligosaccharide catabolic process	Gm2a	IMP	MGI:MGI:1861930	Mouse	PMID:9584189
Biological Process	GO:0051345	positive regulation of hydrolase activity	Gm2a	IDA		Rat	PMID:9770472|RGD:1598995

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern