Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GLDC
  • Mouse genes Gldc
  • Rat genes Gldc
  • Zfish genes gldc
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gldc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	Gldc	IPI	RGD:619946	Rat	PMID:6778858|RGD:1642728
Molecular Function	GO:0016594	glycine binding	Gldc	IDA		Rat	PMID:6778858|RGD:1642728
Molecular Function	GO:0004375	glycine dehydrogenase (decarboxylating) activity	GLDC	IDA		Human	PMID:28244183
Molecular Function	GO:0004375	glycine dehydrogenase (decarboxylating) activity	Gldc	IDA		Rat	PMID:6778858|RGD:1642728
Molecular Function	GO:0030170	pyridoxal phosphate binding	Gldc	IDA		Rat	PMID:6778858|RGD:1642728
Cellular Component	GO:0005960	glycine cleavage complex	Gldc	IDA		Rat	PMID:6778858|RGD:1642728
Cellular Component	GO:0005739	mitochondrion	GLDC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	GLDC	IDA		Human	PMID:28244183
Cellular Component	GO:0005739	mitochondrion	Gldc	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Gldc	IDA		Rat	PMID:6778858|RGD:1642728
Cellular Component	GO:0005654	nucleoplasm	GLDC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	GLDC	IDA		Human	GO_REF:0000052
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Gldc	IEP		Mouse	PMID:20439489
Biological Process	GO:0006546	glycine catabolic process	GLDC	IDA		Human	PMID:28244183
Biological Process	GO:0019464	glycine decarboxylation via glycine cleavage system	Gldc	IDA		Rat	PMID:6778858|RGD:1642728
Biological Process	GO:0065003	protein-containing complex assembly	Gldc	IDA		Rat	PMID:6778858|RGD:1642728

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern