Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GJD3
  • Mouse genes Gjd3
  • Rat genes Gjd3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gjd3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005243	gap junction channel activity	Gjd3	IMP		Rat	PMID:23385797|RGD:7364769
Molecular Function	GO:0086077	gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling	Gjd3	IMP		Mouse	MGI:MGI:5544102|PMID:22982984
Molecular Function	GO:0005216	monoatomic ion channel activity	Gjd3	IGI	MGI:MGI:95718	Mouse	PMID:15879306
Molecular Function	GO:0005216	monoatomic ion channel activity	Gjd3	IDA		Mouse	PMID:15879306
Molecular Function	GO:0005515	protein binding	GJD3	IPI	UniProtKB:Q07157	Human	PMID:12154091
Cellular Component	GO:0009986	cell surface	GJD3	IDA		Human	PMID:12154091
Cellular Component	GO:0005922	connexin complex	GJD3	IDA		Human	PMID:12154091
Cellular Component	GO:0005922	connexin complex	Gjd3	IGI	MGI:MGI:95718	Mouse	PMID:15879306
Cellular Component	GO:0005921	gap junction	Gjd3	IDA		Mouse	PMID:12681499
Biological Process	GO:0086053	AV node cell to bundle of His cell communication by electrical coupling	Gjd3	IMP		Mouse	MGI:MGI:5544102|PMID:22982984
Biological Process	GO:0086053	AV node cell to bundle of His cell communication by electrical coupling	Gjd3	IMP		Mouse	MGI:MGI:3623651|PMID:16571663
Biological Process	GO:0016264	gap junction assembly	GJD3	IDA		Human	PMID:12154091
Biological Process	GO:1903780	negative regulation of cardiac conduction	Gjd3	IMP		Mouse	MGI:MGI:3623651|PMID:16571663
Biological Process	GO:1901845	negative regulation of cell communication by electrical coupling involved in cardiac conduction	Gjd3	IMP		Mouse	MGI:MGI:3623651|PMID:16571663
Biological Process	GO:0010459	negative regulation of heart rate	Gjd3	IMP		Mouse	MGI:MGI:3623651|PMID:16571663
Biological Process	GO:0009749	response to glucose	Gjd3	IDA		Rat	PMID:23385797|RGD:7364769

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern