Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GCSH
  • Mouse genes Gcsh
  • Rat genes Gcsh,RGD1563099
  • Zfish genes gcsha,gcshb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gcsh

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004047	aminomethyltransferase activity	Gcsh	IMP		Rat	PMID:6402507|RGD:1598699
Molecular Function	GO:0019899	enzyme binding	Gcsh	IPI	RGD:1308660	Rat	PMID:6778858|RGD:1642728
Molecular Function	GO:0005515	protein binding	GCSH	IPI	UniProtKB:Q13287	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	GCSH	IPI	UniProtKB:P43360	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GCSH	IPI	UniProtKB:P43364	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GCSH	IPI	UniProtKB:Q13287	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GCSH	IPI	UniProtKB:Q6NTF9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GCSH	IPI	UniProtKB:Q9NYP9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GCSH	IPI	UniProtKB:Q9P086	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GCSH	IPI	UniProtKB:Q9UHD4	Human	PMID:32296183
Cellular Component	GO:0005739	mitochondrion	Gcsh	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Gcsh	IDA		Rat	PMID:6402507|RGD:1598699
Biological Process	GO:0019464	glycine decarboxylation via glycine cleavage system	Gcsh	IMP		Rat	PMID:6402507|RGD:1598699
Biological Process	GO:0009249	protein lipoylation	GCSH	IDA		Human	PMID:1671321

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern