Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GCN1
  • Mouse genes Gcn1
  • Rat genes Gcn1
  • Zfish genes gcn1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gcn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	GCN1	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	Gcn1	IPI	UniProtKB:Q9QZ05	Mouse	MGI:MGI:5576818|PMID:24333428
Molecular Function	GO:0005515	protein binding	Gcn1	IPI	UniProtKB:P25637	Mouse	MGI:MGI:5700292|PMID:22404850
Molecular Function	GO:0005515	protein binding	Gcn1	IPI	PR:O55091	Mouse	PMID:15937339
Molecular Function	GO:0003723	RNA binding	GCN1	HDA		Human	PMID:22681889
Molecular Function	GO:0008494	translation activator activity	Gcn1	IDA		Mouse	MGI:MGI:5576818|PMID:24333428
Cellular Component	GO:0005829	cytosol	GCN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	GCN1	HDA		Human	PMID:19946888
Cellular Component	GO:0005844	polysome	Gcn1	IDA		Mouse	MGI:MGI:5494763|PMID:23447528
Biological Process	GO:0034198	cellular response to amino acid starvation	Gcn1	IDA		Mouse	MGI:MGI:5576818|PMID:24333428
Biological Process	GO:1990253	cellular response to leucine starvation	Gcn1	IDA		Mouse	MGI:MGI:5494763|PMID:23447528

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern