Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GBP6
  • Mouse genes Gbp4
  • Rat genes Gbp6,Gbp6-ps1
  • Zfish genes gbp1,gbp2,si:ch211-209n20.1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gbp4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Gbp4	IPI	PR:P70434	Mouse	PMID:22095711
Cellular Component	GO:0070062	extracellular exosome	GBP6	HDA		Human	PMID:19199708
Biological Process	GO:0071346	cellular response to type II interferon	Gbp4	IDA		Mouse	PMID:18025219
Biological Process	GO:0032687	negative regulation of interferon-alpha production	Gbp4	IMP		Mouse	PMID:22095711
Biological Process	GO:0042308	negative regulation of protein import into nucleus	Gbp4	IDA		Mouse	PMID:22095711
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Gbp4	IDA		Mouse	PMID:22095711
Biological Process	GO:0031397	negative regulation of protein ubiquitination	Gbp4	IGI	MGI:MGI:108072	Mouse	PMID:22095711
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Gbp4	IGI	MGI:MGI:1859212	Mouse	PMID:22095711
Biological Process	GO:0050688	regulation of defense response to virus	Gbp4	IMP		Mouse	PMID:22095711

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern