Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GABBR2
  • Mouse genes Gabbr2
  • Rat genes Gabbr2
  • Zfish genes gabbr2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gabbr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004965	G protein-coupled GABA receptor activity	GABBR2	IDA		Human	PMID:9872316
Molecular Function	GO:0004965	G protein-coupled GABA receptor activity	Gabbr2	IDA		Rat	PMID:11389174|RGD:632824
Molecular Function	GO:0005515	protein binding	GABBR2	IPI	UniProtKB:P46459	Human	PMID:16724110
Molecular Function	GO:0005515	protein binding	GABBR2	IPI	UniProtKB:Q9UBS5	Human	PMID:16724110
Molecular Function	GO:0005515	protein binding	GABBR2	IPI	UniProtKB:Q9UBS5-2	Human	PMID:24305054
Molecular Function	GO:0005515	protein binding	GABBR2	IPI	UniProtKB:Q9UBS5	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	GABBR2	IPI	UniProtKB:Q9UBS5	Human	PMID:32555460
Molecular Function	GO:0005515	protein binding	GABBR2	IPI	UniProtKB:Q9UBS5-2	Human	PMID:32580208
Molecular Function	GO:0005515	protein binding	GABBR2	IPI	UniProtKB:Q9UBS5-2	Human	PMID:32581365
Molecular Function	GO:0005515	protein binding	Gabbr2	IPI	PR:Q06507	Mouse	PMID:15013631
Molecular Function	GO:0005515	protein binding	Gabbr2	IPI	UniProtKB:Q9Z0U4	Rat	PMID:19590495|RGD:8553550
Molecular Function	GO:0005515	protein binding	Gabbr2	IPI	UniProtKB:P27732	Rat	PMID:20627102|RGD:8554172
Molecular Function	GO:0005515	protein binding	Gabbr2	IPI	UniProtKB:Q9Z0U4	Rat	PMID:21063387|RGD:8553604
Molecular Function	GO:0005515	protein binding	Gabbr2	IPI	UniProtKB:Q9Z0U4	Rat	PMID:21552208|RGD:8554334
Molecular Function	GO:0046982	protein heterodimerization activity	GABBR2	IPI	UniProtKB:Q9Z0U4	Human	PMID:15304491
Cellular Component	GO:0005737	cytoplasm	Gabbr2	IDA		Mouse	PMID:15013631
Cellular Component	GO:1902712	G protein-coupled GABA receptor complex	GABBR2	IPI		Human	PMID:24305054
Cellular Component	GO:0038039	G protein-coupled receptor heterodimeric complex	GABBR2	IPI	UniProtKB:Q9UBS5	Human	PMID:9872316
Cellular Component	GO:1902710	GABA receptor complex	GABBR2	IDA		Human	PMID:15304491
Cellular Component	GO:0098982	GABA-ergic synapse	Gabbr2	IDA		Rat	PMID:14657159|RGD:13702400
Cellular Component	GO:0098978	glutamatergic synapse	Gabbr2	IDA		Rat	PMID:14657159|RGD:13702400
Cellular Component	GO:0043005	neuron projection	Gabbr2	IDA		Mouse	PMID:15013631
Cellular Component	GO:0005886	plasma membrane	GABBR2	IDA		Human	PMID:15304491
Cellular Component	GO:0005886	plasma membrane	GABBR2	IDA		Human	PMID:9872316
Cellular Component	GO:0045211	postsynaptic membrane	Gabbr2	IDA		Rat	PMID:14657159|RGD:13702400
Cellular Component	GO:0042734	presynaptic membrane	Gabbr2	IDA		Rat	PMID:14657159|RGD:13702400
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	GABBR2	IDA		Human	PMID:987231
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	Gabbr2	IDA		Rat	PMID:15147298|RGD:2315493
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	GABBR2	IDA		Human	PMID:987231
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	GABBR2	IDA		Human	PMID:9872316
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	Gabbr2	IDA		Rat	PMID:11389174|RGD:632824
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	Gabbr2	IDA		Rat	PMID:15147298|RGD:2315493
Biological Process	GO:0150099	neuron-glial cell signaling	Gabbr2	IGI	UniProtKB:Q9Z0U4	Rat	PMID:10196584|RGD:14397583

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern