Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FRK
  • Mouse genes Frk
  • Rat genes Frk
  • Zfish genes frk
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Frk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FRK	IPI	UniProtKB:P60484	Human	PMID:19345329
Molecular Function	GO:0005515	protein binding	FRK	IPI	UniProtKB:Q12982	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	FRK	IPI	UniProtKB:Q15427	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	FRK	IPI	UniProtKB:Q12982	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FRK	IPI	UniProtKB:Q15427	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FRK	IPI	UniProtKB:Q12982	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FRK	IPI	UniProtKB:Q12982	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FRK	IPI	UniProtKB:P06400	Human	PMID:7664264
Molecular Function	GO:0004713	protein tyrosine kinase activity	FRK	EXP		Human	PMID:19345329
Molecular Function	GO:0004713	protein tyrosine kinase activity	Frk	IDA		Rat	PMID:8760296|RGD:632737
Cellular Component	GO:0005829	cytosol	FRK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	FRK	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	FRK	HDA		Human	PMID:23533145
Cellular Component	GO:0005654	nucleoplasm	FRK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Frk	IDA		Rat	PMID:8760296|RGD:632737
Biological Process	GO:0030154	cell differentiation	Frk	IEP		Rat	PMID:8760296|RGD:632737
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	FRK	IDA		Human	PMID:12837246

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern