Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FREM1
  • Mouse genes Frem1
  • Rat genes Frem1
  • Zfish genes frem1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Frem1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FREM1	IPI	UniProtKB:Q5SZK8	Human	PMID:29688405
Cellular Component	GO:0005604	basement membrane	Frem1	IDA		Mouse	MGI:MGI:3697950|PMID:17251066
Cellular Component	GO:0005604	basement membrane	Frem1	IDA		Mouse	PMID:18757743
Cellular Component	GO:0005604	basement membrane	Frem1	IDA		Mouse	PMID:17596926
Cellular Component	GO:0005604	basement membrane	Frem1	IDA		Mouse	PMID:16880404
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Frem1	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Biological Process	GO:0007160	cell-matrix adhesion	Frem1	IMP	MGI:MGI:3526691	Mouse	PMID:15345741
Biological Process	GO:0097094	craniofacial suture morphogenesis	FREM1	IMP		Human	PMID:21931569
Biological Process	GO:0033333	fin development	frem1a	IMP		Zfish	PMID:9007245
Biological Process	GO:0033334	fin morphogenesis	frem1a	IMP	ZFIN:ZDB-GENO-100528-12	Zfish	PMID:20419147

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern