Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FLVCR1
  • Mouse genes Flvcr1
  • Rat genes Flvcr1
  • Zfish genes flvcr1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Flvcr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015232	heme transmembrane transporter activity	FLVCR1	IMP		Human	PMID:15369674
Molecular Function	GO:0015232	heme transmembrane transporter activity	FLVCR1	IDA		Human	PMID:20610401
Molecular Function	GO:0005515	protein binding	FLVCR1	IPI	UniProtKB:P02790	Human	PMID:20610401
Cellular Component	GO:0005739	mitochondrion	FLVCR1	IDA		Human	PMID:23187127
Biological Process	GO:0001568	blood vessel development	Flvcr1	IMP	MGI:MGI:5474636	Mouse	PMID:23187127
Biological Process	GO:0042733	embryonic digit morphogenesis	Flvcr1	IMP	MGI:MGI:3776021	Mouse	PMID:18258918
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Flvcr1	IMP	MGI:MGI:5474636	Mouse	PMID:23187127
Biological Process	GO:0030218	erythrocyte differentiation	FLVCR1	IDA		Human	PMID:23187127
Biological Process	GO:0030218	erythrocyte differentiation	Flvcr1	IMP	MGI:MGI:3776022	Mouse	PMID:18258918
Biological Process	GO:0030218	erythrocyte differentiation	flvcr1	IMP	ZFIN:ZDB-MRPHLNO-150916-6	Zfish	PMID:25795718
Biological Process	GO:0030218	erythrocyte differentiation	flvcr1	IMP	ZFIN:ZDB-MRPHLNO-150916-4	Zfish	PMID:25795718
Biological Process	GO:0060323	head morphogenesis	Flvcr1	IMP	MGI:MGI:3776021	Mouse	PMID:18258918
Biological Process	GO:0097037	heme export	FLVCR1	IMP		Human	PMID:15369674
Biological Process	GO:0042168	heme metabolic process	flvcr1	IMP	ZFIN:ZDB-MRPHLNO-150916-6	Zfish	PMID:25795718
Biological Process	GO:0042168	heme metabolic process	flvcr1	IMP	ZFIN:ZDB-MRPHLNO-150916-4	Zfish	PMID:25795718
Biological Process	GO:0015886	heme transport	FLVCR1	IMP		Human	PMID:23187127
Biological Process	GO:0001701	in utero embryonic development	Flvcr1	IMP	MGI:MGI:3776021	Mouse	PMID:18258918
Biological Process	GO:0035108	limb morphogenesis	Flvcr1	IMP	MGI:MGI:3776022	Mouse	PMID:18258918
Biological Process	GO:0035108	limb morphogenesis	Flvcr1	IMP	MGI:MGI:3776021	Mouse	PMID:18258918
Biological Process	GO:0006839	mitochondrial transport	FLVCR1	IDA		Human	PMID:23187127
Biological Process	GO:0035264	multicellular organism growth	Flvcr1	IMP	MGI:MGI:3776022	Mouse	PMID:18258918
Biological Process	GO:0046620	regulation of organ growth	Flvcr1	IMP	MGI:MGI:3776022	Mouse	PMID:18258918
Biological Process	GO:0048536	spleen development	Flvcr1	IMP	MGI:MGI:3776022	Mouse	PMID:18258918

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern