Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FEM1B
  • Mouse genes Fem1b
  • Rat genes Fem1b
  • Zfish genes fem1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fem1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005123	death receptor binding	FEM1B	IMP		Human	PMID:10542291
Molecular Function	GO:0005515	protein binding	FEM1B	IPI	UniProtKB:P49593	Human	PMID:11559703
Molecular Function	GO:0005515	protein binding	FEM1B	IPI	UniProtKB:Q9NWT6	Human	PMID:17003112
Molecular Function	GO:0005515	protein binding	FEM1B	IPI	UniProtKB:O14757	Human	PMID:19330022
Molecular Function	GO:0005515	protein binding	Fem1b	IPI	PR:P97436	Mouse	PMID:18816836
Molecular Function	GO:0005515	protein binding	Fem1b	IPI	PR:Q569N2	Mouse	PMID:21723927
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	FEM1B	IDA		Human	PMID:24076122
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	FEM1B	IDA		Human	PMID:29779948
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	FEM1B	IDA		Human	PMID:33398168
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	FEM1B	IDA		Human	PMID:33398170
Cellular Component	GO:0031462	Cul2-RING ubiquitin ligase complex	FEM1B	IDA		Human	PMID:29779948
Cellular Component	GO:0005737	cytoplasm	FEM1B	IDA		Human	PMID:24076122
Cellular Component	GO:0005737	cytoplasm	FEM1B	IDA		Human	PMID:19330022
Cellular Component	GO:0005737	cytoplasm	Fem1b	IDA		Mouse	MGI:MGI:5291895|PMID:21723927
Cellular Component	GO:0005829	cytosol	FEM1B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	FEM1B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	FEM1B	IDA		Human	PMID:19330022
Cellular Component	GO:0005634	nucleus	Fem1b	IDA		Mouse	PMID:19796622
Biological Process	GO:0060442	branching involved in prostate gland morphogenesis	Fem1b	IMP	MGI:MGI:3811024	Mouse	PMID:18816836
Biological Process	GO:0002070	epithelial cell maturation	Fem1b	IMP	MGI:MGI:3811024	Mouse	PMID:18816836
Biological Process	GO:0060743	epithelial cell maturation involved in prostate gland development	Fem1b	IMP	MGI:MGI:3811024	Mouse	PMID:18816836
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	FEM1B	IDA		Human	PMID:24076122
Biological Process	GO:0016567	protein ubiquitination	Fem1b	IDA		Mouse	PMID:21723927
Biological Process	GO:2000001	regulation of DNA damage checkpoint	FEM1B	IMP		Human	PMID:19330022
Biological Process	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	FEM1B	IMP		Human	PMID:10542291
Biological Process	GO:0051438	regulation of ubiquitin-protein transferase activity	FEM1B	IMP		Human	PMID:15601820
Biological Process	GO:0140627	ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	FEM1B	IDA		Human	PMID:29779948
Biological Process	GO:0140627	ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	FEM1B	IDA		Human	PMID:33398168
Biological Process	GO:0140627	ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	FEM1B	IDA		Human	PMID:33398170

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern