Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FDPS
  • Mouse genes Fdps
  • Rat genes Fdps
  • Zfish genes fdps
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fdps

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004337	geranyltranstransferase activity	Fdps	IDA		Rat	PMID:8188698|RGD:2316305
Molecular Function	GO:0005515	protein binding	FDPS	IPI	UniProtKB:P54253	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	FDPS	IPI	UniProtKB:O95870	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FDPS	IPI	UniProtKB:Q6ZMZ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FDPS	IPI	UniProtKB:Q8WWF3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FDPS	IPI	UniProtKB:Q9BRI3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FDPS	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0003723	RNA binding	FDPS	HDA		Human	PMID:22658674
Cellular Component	GO:0005829	cytosol	FDPS	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005759	mitochondrial matrix	Fdps	IDA		Rat	PMID:8119922|RGD:2316297
Cellular Component	GO:0005739	mitochondrion	Fdps	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005654	nucleoplasm	FDPS	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005777	peroxisome	Fdps	IDA		Rat	PMID:10484604|RGD:2316922
Cellular Component	GO:0005777	peroxisome	Fdps	IDA		Rat	PMID:17180682|RGD:8554417
Cellular Component	GO:0005777	peroxisome	Fdps	IDA		Rat	PMID:8188698|RGD:2316305
Biological Process	GO:0071398	cellular response to fatty acid	Fdps	IEP		Rat	PMID:15473864|RGD:2316296
Biological Process	GO:0045337	farnesyl diphosphate biosynthetic process	Fdps	IDA		Rat	PMID:8188698|RGD:2316305
Biological Process	GO:0008584	male gonad development	Fdps	IEP		Rat	PMID:1917693|RGD:2316306
Biological Process	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	Fdps	IMP		Rat	PMID:19716825|RGD:2316294
Biological Process	GO:0045542	positive regulation of cholesterol biosynthetic process	Fdps	IMP		Rat	PMID:18637708|RGD:2316295
Biological Process	GO:0070723	response to cholesterol	Fdps	IEP		Rat	PMID:2909544|RGD:2316308
Biological Process	GO:0043434	response to peptide hormone	Fdps	IEP		Rat	PMID:1917693|RGD:2316306
Biological Process	GO:0033574	response to testosterone	Fdps	IEP		Rat	PMID:12890564|RGD:2316300
Biological Process	GO:0009410	response to xenobiotic stimulus	Fdps	IEP		Rat	PMID:15084352|RGD:2316299
Biological Process	GO:0007283	spermatogenesis	Fdps	IEP		Rat	PMID:2043737|RGD:2316307

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern