Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FANCF
  • Mouse genes Fancf
  • Rat genes Fancf
  • Zfish genes fancf
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fancf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FANCF	IPI	UniProtKB:O15287	Human	PMID:11063725
Molecular Function	GO:0005515	protein binding	FANCF	IPI	UniProtKB:O15360	Human	PMID:11063725
Molecular Function	GO:0005515	protein binding	FANCF	IPI	UniProtKB:O15287	Human	PMID:12649160
Molecular Function	GO:0005515	protein binding	FANCF	IPI	UniProtKB:O15360	Human	PMID:12649160
Molecular Function	GO:0005515	protein binding	FANCF	IPI	UniProtKB:Q8WWU5-7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCF	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Fancf	IMP		Mouse	PMID:21915857
Cellular Component	GO:0000785	chromatin	FANCF	IDA		Human	PMID:22343915
Cellular Component	GO:0043240	Fanconi anaemia nuclear complex	FANCF	IDA		Human	PMID:20347428
Cellular Component	GO:0043240	Fanconi anaemia nuclear complex	Fancf	IMP		Mouse	PMID:21915857
Cellular Component	GO:0005654	nucleoplasm	FANCF	IDA		Human	GO_REF:0000052
Biological Process	GO:0006974	DNA damage response	Fancf	IMP		Mouse	PMID:21915857
Biological Process	GO:0001541	ovarian follicle development	Fancf	IMP		Mouse	PMID:21915857
Biological Process	GO:0006513	protein monoubiquitination	FANCF	IDA		Human	PMID:24910428
Biological Process	GO:0016567	protein ubiquitination	Fancf	IMP		Mouse	PMID:21915857
Biological Process	GO:0007283	spermatogenesis	Fancf	IMP		Mouse	PMID:21915857

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern