Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FAM162A
  • Mouse genes Fam162a
  • Rat genes Fam162a,LOC120095320
  • Zfish genes fam162a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fam162a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FAM162A	IPI	UniProtKB:P45880	Human	PMID:15082785
Molecular Function	GO:0005515	protein binding	FAM162A	IPI	UniProtKB:P08238	Human	PMID:16698020
Cellular Component	GO:0005829	cytosol	FAM162A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	FAM162A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Fam162a	HDA		Mouse	PMID:18614015
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	FAM162A	IDA		Human	PMID:15082785
Biological Process	GO:0071456	cellular response to hypoxia	FAM162A	IDA		Human	PMID:15082785
Biological Process	GO:0071456	cellular response to hypoxia	Fam162a	IDA		Mouse	MGI:MGI:5319611|PMID:17316997
Biological Process	GO:0051402	neuron apoptotic process	Fam162a	IDA		Mouse	MGI:MGI:5319617|PMID:15082785
Biological Process	GO:0051402	neuron apoptotic process	Fam162a	IDA		Mouse	MGI:MGI:5319611|PMID:17316997
Biological Process	GO:0043065	positive regulation of apoptotic process	FAM162A	IDA		Human	PMID:15082785
Biological Process	GO:0043065	positive regulation of apoptotic process	Fam162a	IDA		Mouse	MGI:MGI:5319611|PMID:17316997
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	FAM162A	IDA		Human	PMID:15082785
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	Fam162a	IDA		Mouse	MGI:MGI:5319617|PMID:15082785

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern