Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FA2H
  • Mouse genes Fa2h
  • Rat genes Fa2h
  • Zfish genes fa2h
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fa2h

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0080132	fatty acid alpha-hydroxylase activity	FA2H	IDA		Human	PMID:15337768
Molecular Function	GO:0080132	fatty acid alpha-hydroxylase activity	FA2H	IDA		Human	PMID:15863841
Molecular Function	GO:0080132	fatty acid alpha-hydroxylase activity	FA2H	IMP		Human	PMID:17355976
Molecular Function	GO:0080132	fatty acid alpha-hydroxylase activity	FA2H	IDA		Human	PMID:22517924
Molecular Function	GO:0080132	fatty acid alpha-hydroxylase activity	Fa2h	IDA		Mouse	PMID:15658937
Molecular Function	GO:0080132	fatty acid alpha-hydroxylase activity	Fa2h	IDA		Mouse	PMID:16998236
Molecular Function	GO:0080132	fatty acid alpha-hydroxylase activity	Fa2h	IMP		Rat	PMID:17901466|RGD:13825191
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:O00623	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:O15173	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:O75477	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:O95470	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:P07307-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:P11912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:P21757	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q14973	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q15125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q15700	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q5T0T0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q5T9G4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q7Z5B4-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q8N9I0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q8TED1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q96HV5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q96MV1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q9GZR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q9Y320	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q14204	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FA2H	IPI	UniProtKB:Q92876	Human	PMID:32814053
Cellular Component	GO:0005783	endoplasmic reticulum	Fa2h	IDA		Mouse	PMID:15658937
Cellular Component	GO:0016020	membrane	FA2H	IDA		Human	PMID:15337768
Biological Process	GO:0032286	central nervous system myelin maintenance	Fa2h	IMP	MGI:MGI:4430585	Mouse	PMID:21491498
Biological Process	GO:0032286	central nervous system myelin maintenance	Fa2h	IMP	MGI:MGI:3829000	Mouse	PMID:18815260
Biological Process	GO:0046513	ceramide biosynthetic process	FA2H	IDA		Human	PMID:15337768
Biological Process	GO:0046513	ceramide biosynthetic process	Fa2h	IMP		Mouse	MGI:MGI:6245295|PMID:22517924
Biological Process	GO:0061436	establishment of skin barrier	FA2H	IMP		Human	PMID:17355976
Biological Process	GO:0006631	fatty acid metabolic process	Fa2h	IDA		Mouse	PMID:16998236
Biological Process	GO:0006682	galactosylceramide biosynthetic process	Fa2h	IDA		Mouse	MGI:MGI:3696647|PMID:15658937
Biological Process	GO:0006682	galactosylceramide biosynthetic process	Fa2h	IMP		Mouse	MGI:MGI:3826747|PMID:18815260
Biological Process	GO:0006682	galactosylceramide biosynthetic process	Fa2h	IMP		Rat	PMID:17901466|RGD:13825191
Biological Process	GO:0006679	glucosylceramide biosynthetic process	Fa2h	IMP		Mouse	MGI:MGI:5285470|PMID:21628453
Biological Process	GO:0030258	lipid modification	Fa2h	IDA		Mouse	PMID:15658937
Biological Process	GO:0030258	lipid modification	Fa2h	IMP	MGI:MGI:3829000	Mouse	PMID:18815260
Biological Process	GO:0032287	peripheral nervous system myelin maintenance	Fa2h	IMP	MGI:MGI:3829000	Mouse	PMID:18815260
Biological Process	GO:0044857	plasma membrane raft organization	Fa2h	IMP		Mouse	MGI:MGI:6245295|PMID:22517924
Biological Process	GO:1904697	regulation of acinar cell proliferation	Fa2h	IMP	MGI:MGI:3829000	Mouse	PMID:21628453
Biological Process	GO:0042634	regulation of hair cycle	Fa2h	IMP	MGI:MGI:3829000	Mouse	PMID:21628453
Biological Process	GO:1904002	regulation of sebum secreting cell proliferation	Fa2h	IMP	MGI:MGI:3829000	Mouse	PMID:21628453
Biological Process	GO:0001949	sebaceous gland cell differentiation	Fa2h	IMP	MGI:MGI:3829000	Mouse	PMID:21628453

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern