Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EXTL3
  • Mouse genes Extl3
  • Rat genes Extl3
  • Zfish genes extl3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Extl3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001888	glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	EXTL3	IDA		Human	PMID:11390981
Molecular Function	GO:0001888	glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	EXTL3	IDA		Human	PMID:35676258
Molecular Function	GO:0016757	glycosyltransferase activity	EXTL3	IDA		Human	PMID:28132690
Molecular Function	GO:0016757	glycosyltransferase activity	EXTL3	IDA		Human	PMID:28148688
Molecular Function	GO:0000287	magnesium ion binding	EXTL3	IDA		Human	PMID:35676258
Molecular Function	GO:0005515	protein binding	EXTL3	IPI	UniProtKB:P54253	Human	PMID:32296183
Molecular Function	GO:0016500	protein-hormone receptor activity	Extl3	IDA		Mouse	PMID:28811323
Molecular Function	GO:0016500	protein-hormone receptor activity	Extl3	IDA		Mouse	PMID:27830702
Cellular Component	GO:0005783	endoplasmic reticulum	EXTL3	IDA		Human	PMID:10639137
Cellular Component	GO:0005794	Golgi apparatus	EXTL3	IDA		Human	PMID:28132690
Cellular Component	GO:0016020	membrane	Extl3	IDA		Rat	PMID:10753861|RGD:61576
Cellular Component	GO:0005886	plasma membrane	Extl3	IDA		Mouse	PMID:27830702
Biological Process	GO:0033564	anterior/posterior axon guidance	extl3	IGI	ZFIN:ZDB-GENO-110803-4	Zfish	PMID:19605629
Biological Process	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	extl3	IMP	ZFIN:ZDB-GENO-121010-6	Zfish	PMID:22869369
Biological Process	GO:0035118	embryonic pectoral fin morphogenesis	extl3	IMP	ZFIN:ZDB-GENO-980202-1179	Zfish	PMID:16221725
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	EXTL3	IDA		Human	PMID:11390981
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	EXTL3	IDA		Human	PMID:28132690
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	EXTL3	IDA		Human	PMID:28148688
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	EXTL3	IDA		Human	PMID:35676258
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	Extl3	IMP		Mouse	MGI:MGI:3844390|PMID:19336225
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	extl3	IMP	ZFIN:ZDB-GENO-121010-6	Zfish	PMID:22869369
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	extl3	IMP	ZFIN:ZDB-GENO-980202-1172	Zfish	PMID:15603738
Biological Process	GO:1900016	negative regulation of cytokine production involved in inflammatory response	Extl3	IDA		Mouse	PMID:28811323
Biological Process	GO:0050728	negative regulation of inflammatory response	Extl3	IDA		Mouse	PMID:28811323
Biological Process	GO:0106015	negative regulation of inflammatory response to wounding	Extl3	IDA		Mouse	PMID:27830702
Biological Process	GO:0033339	pectoral fin development	extl3	IMP		Zfish	PMID:9007245
Biological Process	GO:0035138	pectoral fin morphogenesis	extl3	IMP	ZFIN:ZDB-GENO-980202-1172	Zfish	PMID:15603738
Biological Process	GO:0030307	positive regulation of cell growth	Extl3	IDA		Rat	PMID:10753861|RGD:61576
Biological Process	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway	extl3	IMP	ZFIN:ZDB-GENO-980202-1179	Zfish	PMID:16221725
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	Extl3	IDA		Mouse	PMID:27830702
Biological Process	GO:0030516	regulation of axon extension	extl3	IMP	ZFIN:ZDB-GENO-980202-1172	Zfish	PMID:15603738
Biological Process	GO:0031290	retinal ganglion cell axon guidance	extl3	IMP	ZFIN:ZDB-GENO-980202-854	Zfish	PMID:9007260
Biological Process	GO:0031290	retinal ganglion cell axon guidance	extl3	IMP	ZFIN:ZDB-GENO-980202-1178	Zfish	PMID:9007260
Biological Process	GO:0031290	retinal ganglion cell axon guidance	extl3	IMP	ZFIN:ZDB-GENO-980202-1180	Zfish	PMID:9007260
Biological Process	GO:0031290	retinal ganglion cell axon guidance	extl3	IMP	ZFIN:ZDB-GENO-980202-1177	Zfish	PMID:9007260
Biological Process	GO:0031290	retinal ganglion cell axon guidance	extl3	IMP	ZFIN:ZDB-GENO-980202-1172	Zfish	PMID:9007260
Biological Process	GO:0031290	retinal ganglion cell axon guidance	extl3	IMP	ZFIN:ZDB-GENO-980202-1179	Zfish	PMID:9007260
Biological Process	GO:0031290	retinal ganglion cell axon guidance	extl3	IMP	ZFIN:ZDB-GENO-980202-1176	Zfish	PMID:9007260
Biological Process	GO:0031290	retinal ganglion cell axon guidance	extl3	IMP	ZFIN:ZDB-GENO-980202-1181	Zfish	PMID:9007260
Biological Process	GO:0048538	thymus development	extl3	IMP	ZFIN:ZDB-GENO-980202-1172	Zfish	PMID:28148688

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern