Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EXOSC4
  • Mouse genes Exosc4
  • Rat genes Exosc4
  • Zfish genes exosc4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Exosc4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	EXOSC4	IDA		Human	PMID:16912217
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q13868	Human	PMID:11719186
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q13868	Human	PMID:12419256
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q15024	Human	PMID:12419256
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q06265	Human	PMID:12788944
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q9Y3B2	Human	PMID:12788944
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q01780	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q06265	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q9NQT5	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q9Y3B2	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q13868	Human	PMID:17545563
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q01780	Human	PMID:20531386
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q06265	Human	PMID:20531386
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q13868	Human	PMID:20531386
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q15024	Human	PMID:20531386
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q8TF46	Human	PMID:20531386
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q9NQT5	Human	PMID:20531386
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q9Y3B2	Human	PMID:20531386
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q9NQT5	Human	PMID:20531389
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q01780	Human	PMID:21255825
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q9NQT5	Human	PMID:21255825
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q8IY21	Human	PMID:21791617
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q01780	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q06265	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q13868	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q15024	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q9NQT5	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q9Y3B2	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q9Y3B2	Human	PMID:25043052
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q15024	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q01780	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q06265	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q13868	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q15024	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q9NQT5	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q9Y3B2	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q15024	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q9NQT5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q9Y3B2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q06265	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:P56282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC4	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Exosc4	IPI	UniProtKB:E9PZQ1	Mouse	PMID:21791617
Cellular Component	GO:0005737	cytoplasm	EXOSC4	IDA		Human	PMID:17545563
Cellular Component	GO:0005829	cytosol	EXOSC4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	EXOSC4	IDA		Human	PMID:20531386
Cellular Component	GO:0000791	euchromatin	EXOSC4	IMP		Human	PMID:20699273
Cellular Component	GO:0000178	exosome (RNase complex)	EXOSC4	IDA		Human	PMID:20531389
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	EXOSC4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	EXOSC4	IDA		Human	PMID:20531386
Cellular Component	GO:0005654	nucleoplasm	EXOSC4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	EXOSC4	IDA		Human	PMID:17545563
Cellular Component	GO:0005634	nucleus	EXOSC4	IDA		Human	PMID:20531386
Biological Process	GO:0051607	defense response to virus	EXOSC4	IMP		Human	PMID:21791617
Biological Process	GO:0045006	DNA deamination	EXOSC4	IDA		Human	PMID:21255825
Biological Process	GO:0071044	histone mRNA catabolic process	EXOSC4	IMP		Human	PMID:18172165
Biological Process	GO:0000460	maturation of 5.8S rRNA	EXOSC4	IMP		Human	PMID:20368444
Biological Process	GO:0071028	nuclear mRNA surveillance	EXOSC4	IMP		Human	PMID:17545563
Biological Process	GO:0000956	nuclear-transcribed mRNA catabolic process	EXOSC4	IMP		Human	PMID:17545563
Biological Process	GO:0030307	positive regulation of cell growth	EXOSC4	IMP		Human	PMID:17545563
Biological Process	GO:0006401	RNA catabolic process	EXOSC4	IDA		Human	PMID:17174896
Biological Process	GO:0006401	RNA catabolic process	EXOSC4	IDA		Human	PMID:20531386
Biological Process	GO:0006396	RNA processing	EXOSC4	IDA		Human	PMID:17174896
Biological Process	GO:0006396	RNA processing	EXOSC4	IDA		Human	PMID:20531386

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern