Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EXOSC10
  • Mouse genes Exosc10
  • Rat genes Exosc10
  • Zfish genes exosc10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Exosc10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	EXOSC10	IMP		Human	PMID:26950371
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q9H2U1	Human	PMID:14731398
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q99547	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q9NPD3	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q9NQT4	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q9Y2L1	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q99547	Human	PMID:16396833
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q86V81	Human	PMID:17234882
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q13901	Human	PMID:17412707
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q99547	Human	PMID:17412707
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q9NPD3	Human	PMID:20531386
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q9Y2L1	Human	PMID:20531386
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q9NPD3	Human	PMID:21255825
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q9NQT4	Human	PMID:21255825
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q9Y2L1	Human	PMID:21255825
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:P17844	Human	PMID:23143267
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q9Y2L1	Human	PMID:23756462
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q9NPD3	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q9NQT4	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q9NPD3	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q9NQT4	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC10	IPI	UniProtKB:Q9H7Z3	Human	PMID:30538148
Molecular Function	GO:0003723	RNA binding	EXOSC10	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	EXOSC10	HDA		Human	PMID:22681889
Molecular Function	GO:0004532	RNA exonuclease activity	EXOSC10	IDA		Human	PMID:17174896
Cellular Component	GO:0005737	cytoplasm	EXOSC10	IDA		Human	PMID:17545563
Cellular Component	GO:0005737	cytoplasm	EXOSC10	IDA		Human	PMID:20531386
Cellular Component	GO:0005829	cytosol	EXOSC10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	EXOSC10	IDA		Human	PMID:20531386
Cellular Component	GO:0000791	euchromatin	EXOSC10	IMP		Human	PMID:20699273
Cellular Component	GO:0000178	exosome (RNase complex)	EXOSC10	IDA		Human	PMID:20531389
Cellular Component	GO:0016020	membrane	EXOSC10	HDA		Human	PMID:19946888
Cellular Component	GO:0000176	nuclear exosome (RNase complex)	EXOSC10	IDA		Human	PMID:26166824
Cellular Component	GO:0005730	nucleolus	EXOSC10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	EXOSC10	IDA		Human	PMID:20531386
Cellular Component	GO:0005654	nucleoplasm	EXOSC10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	EXOSC10	IDA		Human	PMID:17545563
Cellular Component	GO:0005634	nucleus	EXOSC10	IDA		Human	PMID:20531386
Biological Process	GO:0071034	CUT catabolic process	EXOSC10	IMP		Human	PMID:19056938
Biological Process	GO:0009048	dosage compensation by inactivation of X chromosome	Exosc10	IMP		Mouse	PMID:16789828
Biological Process	GO:0071044	histone mRNA catabolic process	EXOSC10	IMP		Human	PMID:18172165
Biological Process	GO:0000460	maturation of 5.8S rRNA	EXOSC10	IMP		Human	PMID:17412707
Biological Process	GO:0000460	maturation of 5.8S rRNA	EXOSC10	IMP		Human	PMID:20368444
Biological Process	GO:0032211	negative regulation of telomere maintenance via telomerase	EXOSC10	IMP		Human	PMID:26950371
Biological Process	GO:0071028	nuclear mRNA surveillance	EXOSC10	IMP		Human	PMID:17545563
Biological Process	GO:0071028	nuclear mRNA surveillance	EXOSC10	IMP		Human	PMID:20699273
Biological Process	GO:0071035	nuclear polyadenylation-dependent rRNA catabolic process	EXOSC10	IMP		Human	PMID:16455498
Biological Process	GO:0000956	nuclear-transcribed mRNA catabolic process	EXOSC10	IMP		Human	PMID:17545563
Biological Process	GO:1904872	regulation of telomerase RNA localization to Cajal body	EXOSC10	IMP		Human	PMID:26950371
Biological Process	GO:0006401	RNA catabolic process	EXOSC10	IDA		Human	PMID:17174896
Biological Process	GO:0006401	RNA catabolic process	EXOSC10	IDA		Human	PMID:20531386
Biological Process	GO:0006396	RNA processing	EXOSC10	IDA		Human	PMID:17174896
Biological Process	GO:0006396	RNA processing	EXOSC10	IDA		Human	PMID:20531386

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern