Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EXOSC1
  • Mouse genes Exosc1
  • Rat genes Exosc1
  • Zfish genes exosc1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Exosc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q15024	Human	PMID:11812149
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NQT4	Human	PMID:11812149
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q15024	Human	PMID:12419256
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NQT4	Human	PMID:12419256
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q15024	Human	PMID:12788944
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NPD3	Human	PMID:12788944
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q96B26	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NPD3	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NQT4	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NQT4	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NPD3	Human	PMID:20531386
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q8IY21	Human	PMID:21791617
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NPD3	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NQT4	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q15024	Human	PMID:25043052
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q96B26	Human	PMID:25043052
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NPD3	Human	PMID:25043052
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NQT4	Human	PMID:25043052
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:P15884	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q04864	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q719H9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NQT4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9P286	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q15024	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q96B26	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NPD3	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NQT4	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NQT4	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q15024	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q96B26	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NPD3	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NQT4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:P15884	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q04864	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NQT4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:P36508	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:P52747	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q04864-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q719H9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q96B26	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q96DX5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC1	IPI	UniProtKB:Q9NQT4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Exosc1	IPI	UniProtKB:E9PZQ1	Mouse	PMID:21791617
Cellular Component	GO:0005829	cytosol	EXOSC1	IDA		Human	PMID:20531386
Cellular Component	GO:0000178	exosome (RNase complex)	EXOSC1	IDA		Human	PMID:20531389
Cellular Component	GO:0005730	nucleolus	EXOSC1	IDA		Human	PMID:11812149
Cellular Component	GO:0005730	nucleolus	EXOSC1	IDA		Human	PMID:20531386
Cellular Component	GO:0005634	nucleus	EXOSC1	IDA		Human	PMID:20531386
Biological Process	GO:0006401	RNA catabolic process	EXOSC1	IDA		Human	PMID:17174896
Biological Process	GO:0006401	RNA catabolic process	EXOSC1	IDA		Human	PMID:20531386
Biological Process	GO:0006396	RNA processing	EXOSC1	IDA		Human	PMID:17174896
Biological Process	GO:0006396	RNA processing	EXOSC1	IDA		Human	PMID:20531386

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern