Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EXO1
  • Mouse genes Exo1
  • Rat genes Exo1
  • Zfish genes exo1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Exo1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035312	5'-3' DNA exonuclease activity	EXO1	IDA		Human	PMID:10608837
Molecular Function	GO:0003682	chromatin binding	Exo1	IDA		Mouse	PMID:14716311
Molecular Function	GO:0003677	DNA binding	EXO1	IDA		Human	PMID:11842105
Molecular Function	GO:0051908	double-stranded DNA 5'-3' exodeoxyribonuclease activity	EXO1	IDA		Human	PMID:10608837
Molecular Function	GO:0051908	double-stranded DNA 5'-3' exodeoxyribonuclease activity	EXO1	IDA		Human	PMID:11842105
Molecular Function	GO:0048256	flap endonuclease activity	EXO1	IDA		Human	PMID:10608837
Molecular Function	GO:0048256	flap endonuclease activity	EXO1	IDA		Human	PMID:11842105
Molecular Function	GO:0005515	protein binding	EXO1	IPI	UniProtKB:P43246	Human	PMID:10856833
Molecular Function	GO:0005515	protein binding	EXO1	IPI	UniProtKB:P20585	Human	PMID:11427529
Molecular Function	GO:0005515	protein binding	EXO1	IPI	UniProtKB:P40692	Human	PMID:11427529
Molecular Function	GO:0005515	protein binding	EXO1	IPI	UniProtKB:P43246	Human	PMID:11427529
Molecular Function	GO:0005515	protein binding	EXO1	IPI	UniProtKB:P40692	Human	PMID:11429708
Molecular Function	GO:0005515	protein binding	EXO1	IPI	UniProtKB:P43246	Human	PMID:11429708
Molecular Function	GO:0005515	protein binding	EXO1	IPI	UniProtKB:P43246	Human	PMID:12414623
Molecular Function	GO:0005515	protein binding	EXO1	IPI	UniProtKB:P40692	Human	PMID:14676842
Molecular Function	GO:0005515	protein binding	EXO1	IPI	UniProtKB:P43246	Human	PMID:14676842
Molecular Function	GO:0005515	protein binding	EXO1	IPI	UniProtKB:P12004	Human	PMID:15225546
Molecular Function	GO:0005515	protein binding	EXO1	IPI	UniProtKB:P46063	Human	PMID:15886194
Molecular Function	GO:0005515	protein binding	EXO1	IPI	UniProtKB:Q99708	Human	PMID:21052091
Molecular Function	GO:0005515	protein binding	EXO1	IPI	UniProtKB:P40692	Human	PMID:2414623
Molecular Function	GO:0005515	protein binding	EXO1	IPI	UniProtKB:Q99708	Human	PMID:26807646
Molecular Function	GO:0005515	protein binding	EXO1	IPI	UniProtKB:P43246	Human	PMID:9788596
Molecular Function	GO:0045145	single-stranded DNA 5'-3' DNA exonuclease activity	EXO1	IDA		Human	PMID:10608837
Cellular Component	GO:0016604	nuclear body	EXO1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	EXO1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	EXO1	IDA		Human	PMID:11429708
Cellular Component	GO:0005634	nucleus	EXO1	IDA		Human	PMID:14676842
Cellular Component	GO:0005886	plasma membrane	EXO1	IDA		Human	GO_REF:0000052
Biological Process	GO:0006310	DNA recombination	EXO1	IGI	UniProtKB:P39875	Human	PMID:10364235
Biological Process	GO:0002455	humoral immune response mediated by circulating immunoglobulin	Exo1	IMP	MGI:MGI:2653925	Mouse	PMID:14716311
Biological Process	GO:0045190	isotype switching	Exo1	IMP	MGI:MGI:2653925	Mouse	PMID:14716311
Biological Process	GO:0006298	mismatch repair	EXO1	IMP		Human	PMID:11809771
Biological Process	GO:0006298	mismatch repair	EXO1	IDA		Human	PMID:14636568
Biological Process	GO:0006298	mismatch repair	EXO1	IPI	UniProtKB:P43246	Human	PMID:9788596
Biological Process	GO:0016446	somatic hypermutation of immunoglobulin genes	Exo1	IMP	MGI:MGI:2653925	Mouse	PMID:14716311

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern