Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ERBIN
  • Mouse genes Erbin
  • Rat genes Erbin
  • Zfish genes erbin
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Erbin

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ERBIN	IPI	UniProtKB:Q03001	Human	PMID:11375975
Molecular Function	GO:0005515	protein binding	ERBIN	IPI	UniProtKB:Q99569	Human	PMID:12047349
Molecular Function	GO:0005515	protein binding	ERBIN	IPI	UniProtKB:Q99569	Human	PMID:16203728
Molecular Function	GO:0005515	protein binding	ERBIN	IPI	UniProtKB:Q9HC29	Human	PMID:16203728
Molecular Function	GO:0005515	protein binding	ERBIN	IPI	UniProtKB:Q9HC29	Human	PMID:16714539
Molecular Function	GO:0005515	protein binding	ERBIN	IPI	UniProtKB:Q99569	Human	PMID:24550280
Molecular Function	GO:0005515	protein binding	ERBIN	IPI	UniProtKB:Q9HC29	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	Erbin	IPI	PR:P70424	Mouse	PMID:10878805
Molecular Function	GO:0005102	signaling receptor binding	ERBIN	IPI	UniProtKB:Q9HC29	Human	PMID:16203728
Cellular Component	GO:0016323	basolateral plasma membrane	ERBIN	IDA		Human	PMID:16203728
Cellular Component	GO:0016323	basolateral plasma membrane	Erbin	IDA		Mouse	PMID:10878805
Cellular Component	GO:0030054	cell junction	ERBIN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	ERBIN	IDA		Human	PMID:11375975
Cellular Component	GO:0098978	glutamatergic synapse	Erbin	IDA		Mouse	PMID:23354328
Cellular Component	GO:0098978	glutamatergic synapse	Erbin	IMP		Mouse	PMID:23354328
Cellular Component	GO:0098978	glutamatergic synapse	Erbin	IDA		Rat	PMID:11279080|RGD:13702240
Cellular Component	GO:0098978	glutamatergic synapse	Erbin	IMP		Rat	PMID:11279080|RGD:13702240
Cellular Component	GO:0030056	hemidesmosome	ERBIN	IDA		Human	PMID:11375975
Cellular Component	GO:0031594	neuromuscular junction	Erbin	IDA		Rat	PMID:11279080|RGD:13702240
Cellular Component	GO:0031594	neuromuscular junction	Erbin	IMP		Rat	PMID:11279080|RGD:13702240
Cellular Component	GO:0016607	nuclear speck	ERBIN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ERBIN	IDA		Human	PMID:11375975
Cellular Component	GO:0005886	plasma membrane	ERBIN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098794	postsynapse	Erbin	IDA		Mouse	PMID:23354328
Cellular Component	GO:0099572	postsynaptic specialization	Erbin	IDA		Rat	PMID:11279080|RGD:13702240
Cellular Component	GO:0099572	postsynaptic specialization	Erbin	IMP		Rat	PMID:11279080|RGD:13702240
Biological Process	GO:0071356	cellular response to tumor necrosis factor	ERBIN	IMP		Human	PMID:16203728
Biological Process	GO:0071638	negative regulation of monocyte chemotactic protein-1 production	Erbin	IMP	UniProtKB:Q8K3Z0	Mouse	MGI:MGI:5640951|PMID:16203728
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	ERBIN	IMP		Human	PMID:16203728
Biological Process	GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	ERBIN	IMP		Human	PMID:16203728
Biological Process	GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	Erbin	IMP		Mouse	MGI:MGI:5640951|PMID:16203728
Biological Process	GO:0006605	protein targeting	Erbin	IDA		Mouse	PMID:10878805
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Erbin	IDA		Mouse	PMID:23354328
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Erbin	IMP		Mouse	PMID:23354328
Biological Process	GO:0032496	response to lipopolysaccharide	ERBIN	IMP		Human	PMID:16203728
Biological Process	GO:0032495	response to muramyl dipeptide	ERBIN	IMP		Human	PMID:16203728

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern