Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EPS15L1
  • Mouse genes Eps15l1
  • Rat genes Eps15l1
  • Zfish genes eps15l1a,eps15l1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eps15l1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	EPS15L1	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	EPS15L1	IPI	UniProtKB:Q9UMX0	Human	PMID:16159959
Molecular Function	GO:0005515	protein binding	EPS15L1	IPI	UniProtKB:Q969G5	Human	PMID:19262564
Molecular Function	GO:0005515	protein binding	EPS15L1	IPI	UniProtKB:P0DI81	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EPS15L1	IPI	UniProtKB:P63218	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Eps15l1	IPI	UniProtKB:P98078	Mouse	MGI:MGI:5448497|PMID:22648170
Molecular Function	GO:0005515	protein binding	Eps15l1	IPI	UniProtKB:P42567	Mouse	MGI:MGI:3687718|PMID:9446614
Cellular Component	GO:0030132	clathrin coat of coated pit	Eps15l1	IDA		Mouse	PMID:18434600
Cellular Component	GO:0016020	membrane	EPS15L1	HDA		Human	PMID:19946888
Biological Process	GO:0033077	T cell differentiation in thymus	eps15l1b	IMP	ZFIN:ZDB-GENO-160714-21	Zfish	PMID:26161877

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern