Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ENPP3
  • Mouse genes Enpp3
  • Rat genes Enpp3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Enpp3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	ENPP3	IDA		Human	PMID:29717535
Molecular Function	GO:0047429	nucleoside triphosphate diphosphatase activity	ENPP3	IDA		Human	PMID:10513816
Molecular Function	GO:0047429	nucleoside triphosphate diphosphatase activity	ENPP3	IDA		Human	PMID:29717535
Molecular Function	GO:0047429	nucleoside triphosphate diphosphatase activity	Enpp3	IMP		Mouse	MGI:MGI:5660449|PMID:25692702
Molecular Function	GO:0004528	phosphodiesterase I activity	ENPP3	IMP		Human	PMID:11342463
Molecular Function	GO:0008270	zinc ion binding	ENPP3	IDA		Human	PMID:29717535
Cellular Component	GO:0009897	external side of plasma membrane	ENPP3	IDA		Human	PMID:11342463
Cellular Component	GO:0009897	external side of plasma membrane	Enpp3	IDA		Mouse	MGI:MGI:5660449|PMID:25692702
Cellular Component	GO:0070062	extracellular exosome	ENPP3	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ENPP3	HDA		Human	PMID:19199708
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ENPP3	IDA		Human	PMID:10513816
Biological Process	GO:0046034	ATP metabolic process	ENPP3	IDA		Human	PMID:29717535
Biological Process	GO:0046034	ATP metabolic process	Enpp3	IMP		Mouse	MGI:MGI:5660449|PMID:25692702
Biological Process	GO:0002276	basophil activation involved in immune response	Enpp3	IMP		Mouse	MGI:MGI:5660449|PMID:25692702
Biological Process	GO:0050728	negative regulation of inflammatory response	Enpp3	IMP		Mouse	MGI:MGI:5660449|PMID:25692702
Biological Process	GO:0033007	negative regulation of mast cell activation involved in immune response	Enpp3	IMP		Mouse	MGI:MGI:5660449|PMID:25692702
Biological Process	GO:0070667	negative regulation of mast cell proliferation	Enpp3	IMP		Mouse	MGI:MGI:5660449|PMID:25692702
Biological Process	GO:0009143	nucleoside triphosphate catabolic process	ENPP3	IDA		Human	PMID:10513816
Biological Process	GO:0055062	phosphate ion homeostasis	Enpp3	IDA		Mouse	PMID:21490328
Biological Process	GO:0006796	phosphate-containing compound metabolic process	ENPP3	IDA		Human	PMID:10513816
Biological Process	GO:0006220	pyrimidine nucleotide metabolic process	ENPP3	IMP		Human	PMID:11342463

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern