Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ELOVL1
  • Mouse genes Elovl1
  • Rat genes Elovl1
  • Zfish genes elovl1a,elovl1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Elovl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0009922	fatty acid elongase activity	ELOVL1	EXP		Human	PMID:10970790
Molecular Function	GO:0009922	fatty acid elongase activity	ELOVL1	IDA		Human	PMID:20166112
Molecular Function	GO:0005515	protein binding	ELOVL1	IPI	UniProtKB:Q53GQ0	Human	PMID:20937905
Molecular Function	GO:0005515	protein binding	ELOVL1	IPI	UniProtKB:Q96G23	Human	PMID:20937905
Molecular Function	GO:0005515	protein binding	ELOVL1	IPI	UniProtKB:Q99190	Human	PMID:20937905
Cellular Component	GO:0005783	endoplasmic reticulum	ELOVL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	ELOVL1	IDA		Human	PMID:20937905
Cellular Component	GO:0016020	membrane	ELOVL1	HDA		Human	PMID:19946888
Biological Process	GO:0046513	ceramide biosynthetic process	Elovl1	IMP		Mouse	MGI:MGI:5532629|PMID:23689133
Biological Process	GO:0061436	establishment of skin barrier	Elovl1	IMP		Mouse	MGI:MGI:5532629|PMID:23689133
Biological Process	GO:0034625	fatty acid elongation, monounsaturated fatty acid	ELOVL1	IDA		Human	PMID:20166112
Biological Process	GO:0019367	fatty acid elongation, saturated fatty acid	ELOVL1	IDA		Human	PMID:20166112
Biological Process	GO:0019367	fatty acid elongation, saturated fatty acid	ELOVL1	IDA		Human	PMID:20937905
Biological Process	GO:0001822	kidney development	elovl1b	IMP	ZFIN:ZDB-MRPHLNO-160916-4	Zfish	PMID:27078170
Biological Process	GO:0001822	kidney development	elovl1b	IMP	ZFIN:ZDB-MRPHLNO-160916-5	Zfish	PMID:27078170
Biological Process	GO:0030148	sphingolipid biosynthetic process	ELOVL1	IMP		Human	PMID:20937905
Biological Process	GO:0030148	sphingolipid biosynthetic process	Elovl1	IMP		Mouse	MGI:MGI:4944052|PMID:20253178
Biological Process	GO:0048794	swim bladder development	elovl1b	IGI	ZFIN:ZDB-MRPHLNO-160916-2,ZFIN:ZDB-MRPHLNO-160916-4	Zfish	PMID:27078170
Biological Process	GO:0048794	swim bladder development	elovl1b	IGI	ZFIN:ZDB-MRPHLNO-160916-3,ZFIN:ZDB-MRPHLNO-160916-5	Zfish	PMID:27078170
Biological Process	GO:0048794	swim bladder development	elovl1a	IGI	ZFIN:ZDB-MRPHLNO-160916-2,ZFIN:ZDB-MRPHLNO-160916-4	Zfish	PMID:27078170
Biological Process	GO:0048794	swim bladder development	elovl1a	IGI	ZFIN:ZDB-MRPHLNO-160916-3,ZFIN:ZDB-MRPHLNO-160916-5	Zfish	PMID:27078170
Biological Process	GO:0042761	very long-chain fatty acid biosynthetic process	ELOVL1	IDA		Human	PMID:20166112
Biological Process	GO:0042761	very long-chain fatty acid biosynthetic process	ELOVL1	IDA		Human	PMID:20937905

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern