Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ELAC2
  • Mouse genes Elac2
  • Rat genes Elac2
  • Zfish genes elac2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Elac2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003723	RNA binding	ELAC2	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	ELAC2	HDA		Human	PMID:22681889
Molecular Function	GO:0004549	tRNA-specific ribonuclease activity	ELAC2	EXP		Human	PMID:12711671
Molecular Function	GO:0004549	tRNA-specific ribonuclease activity	ELAC2	EXP		Human	PMID:15317868
Molecular Function	GO:0004549	tRNA-specific ribonuclease activity	ELAC2	EXP		Human	PMID:16361254
Molecular Function	GO:0004549	tRNA-specific ribonuclease activity	ELAC2	EXP		Human	PMID:18809514
Molecular Function	GO:0004549	tRNA-specific ribonuclease activity	ELAC2	EXP		Human	PMID:21559454
Molecular Function	GO:0004549	tRNA-specific ribonuclease activity	ELAC2	EXP		Human	PMID:21593607
Cellular Component	GO:0042645	mitochondrial nucleoid	ELAC2	IDA		Human	PMID:24703694
Cellular Component	GO:0042645	mitochondrial nucleoid	Elac2	IDA		Mouse	PMID:24703694
Cellular Component	GO:0005739	mitochondrion	ELAC2	IDA		Human	PMID:21593607
Cellular Component	GO:0005739	mitochondrion	Elac2	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005654	nucleoplasm	ELAC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ELAC2	IDA		Human	PMID:21593607
Biological Process	GO:0072684	mitochondrial tRNA 3'-trailer cleavage, endonucleolytic	ELAC2	IMP		Human	PMID:21593607

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern