Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EIF4G3
  • Mouse genes Eif4g3
  • Rat genes Eif4g3
  • Zfish genes eif4g3a,eif4g3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eif4g3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EIF4G3	IPI	UniProtKB:P06730	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EIF4G3	IPI	UniProtKB:P06730	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EIF4G3	IPI	UniProtKB:P06730	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Eif4g3	IPI	UniProtKB:Q8CDG1	Mouse	MGI:MGI:3842880|PMID:19114715
Molecular Function	GO:0003723	RNA binding	EIF4G3	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	EIF4G3	HDA		Human	PMID:22681889
Molecular Function	GO:0003743	translation initiation factor activity	Eif4g3	IDA		Mouse	PMID:35951695
Cellular Component	GO:0043232	intracellular non-membrane-bounded organelle	Eif4g3	IDA		Mouse	PMID:35951695
Cellular Component	GO:0045202	synapse	Eif4g3	IDA		Mouse	PMID:25211037
Cellular Component	GO:0045202	synapse	Eif4g3	EXP		Mouse	PMID:25211037
Biological Process	GO:0060903	positive regulation of meiosis I	Eif4g3	IMP	MGI:MGI:3512906	Mouse	PMID:20430745
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Eif4g3	IMP	MGI:MGI:3512906	Mouse	PMID:20430745
Biological Process	GO:0045727	positive regulation of translation	Eif4g3	IDA		Mouse	PMID:35951695
Biological Process	GO:0045727	positive regulation of translation	Eif4g3	IMP	MGI:MGI:3512906	Mouse	PMID:20430745
Biological Process	GO:0007286	spermatid development	Eif4g3	IDA		Mouse	PMID:35951695
Biological Process	GO:0007283	spermatogenesis	Eif4g3	IMP	MGI:MGI:3512906	Mouse	PMID:20430745
Biological Process	GO:0006412	translation	Eif4g3	IMP	MGI:MGI:3512906	Mouse	PMID:20430745

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern