Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EIF4A1
  • Mouse genes Eif4a1
  • Rat genes Eif4a1
  • Zfish genes eif4a1a,eif4a1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eif4a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003725	double-stranded RNA binding	EIF4A1	IDA		Human	PMID:21266579
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:P78344	Human	PMID:16166382
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:P78344	Human	PMID:16932749
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:Q04637	Human	PMID:16932749
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:Q9BWF3	Human	PMID:17284590
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:Q9BWF3-1	Human	PMID:17284590
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:Q53EL6	Human	PMID:18296639
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:Q04637	Human	PMID:18606994
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:Q04637-1	Human	PMID:18606994
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:Q04637	Human	PMID:19203580
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:Q15056	Human	PMID:19203580
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:Q53EL6	Human	PMID:19204291
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:Q9BWF3-1	Human	PMID:22678294
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:Q04637	Human	PMID:23023399
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:P78344-1	Human	PMID:23478064
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:Q04637	Human	PMID:23478064
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:Q53EL6	Human	PMID:24413684
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:Q53EL6	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EIF4A1	IPI	UniProtKB:Q9H074	Human	PMID:9548260
Molecular Function	GO:0005515	protein binding	Eif4a1	IPI	UniProtKB:Q61823|UniProtKB:Q6NZJ6	Mouse	MGI:MGI:3836198|PMID:19153607
Molecular Function	GO:0005515	protein binding	Eif4a1	IPI	UniProtKB:Q6NZJ6	Mouse	MGI:MGI:3628832|PMID:16541103
Molecular Function	GO:0003723	RNA binding	EIF4A1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	EIF4A1	HDA		Human	PMID:22681889
Molecular Function	GO:0003743	translation initiation factor activity	EIF4A1	IDA		Human	PMID:34731628
Cellular Component	GO:0005737	cytoplasm	EIF4A1	IDA		Human	PMID:12426392
Cellular Component	GO:0070062	extracellular exosome	EIF4A1	HDA		Human	PMID:20458337
Cellular Component	GO:0016020	membrane	EIF4A1	HDA		Human	PMID:19946888
Biological Process	GO:0002183	cytoplasmic translational initiation	EIF4A1	IDA		Human	PMID:34731628

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern