Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EIF3L
  • Mouse genes Eif3l
  • Rat genes Eif3l
  • Zfish genes eif3s6ip
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eif3l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EIF3L	IPI	UniProtKB:Q9UBQ5	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	EIF3L	IPI	UniProtKB:P55884	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3L	IPI	UniProtKB:P60228	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3L	IPI	UniProtKB:Q9UBQ5	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3L	IPI	UniProtKB:P60228	Human	PMID:19748344
Molecular Function	GO:0005515	protein binding	EIF3L	IPI	UniProtKB:Q9UBQ5	Human	PMID:19748344
Molecular Function	GO:0005515	protein binding	EIF3L	IPI	UniProtKB:Q9UBQ5	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	EIF3L	IPI	UniProtKB:Q9Q2G4	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	EIF3L	IPI	UniProtKB:P60228	Human	PMID:23623729
Molecular Function	GO:0005515	protein binding	EIF3L	IPI	UniProtKB:Q9UBQ5	Human	PMID:23623729
Molecular Function	GO:0005515	protein binding	EIF3L	IPI	UniProtKB:P19712:PRO_0000038050	Human	PMID:24965446
Molecular Function	GO:0005515	protein binding	EIF3L	IPI	UniProtKB:Q9UBQ5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EIF3L	IPI	UniProtKB:P60228	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EIF3L	IPI	UniProtKB:Q9UBQ5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EIF3L	IPI	UniProtKB:Q6NYC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF3L	IPI	UniProtKB:Q9UBQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF3L	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Eif3l	IPI	PR:P25976	Mouse	PMID:11592397
Molecular Function	GO:0005515	protein binding	Eif3l	IPI	PR:P70700	Mouse	PMID:11592397
Molecular Function	GO:0005515	protein binding	Eif3l	IPI	PR:Q8K202	Mouse	PMID:11592397
Molecular Function	GO:0003723	RNA binding	EIF3L	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	EIF3L	HDA		Human	PMID:22681889
Molecular Function	GO:0003743	translation initiation factor activity	EIF3L	IDA		Human	PMID:17581632
Molecular Function	GO:0003743	translation initiation factor activity	EIF3L	IDA		Human	PMID:25849773
Molecular Function	GO:0003743	translation initiation factor activity	Eif3l	IDA		Mouse	MGI:MGI:3843422|PMID:17581632
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3L	IPI		Human	PMID:17322308
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3L	IDA		Human	PMID:17322308
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3L	IDA		Human	PMID:17581632
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3L	IDA		Human	PMID:18599441
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3L	IDA		Human	PMID:25849773
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	Eif3l	IDA		Mouse	MGI:MGI:3843422|PMID:17581632
Cellular Component	GO:0001650	fibrillar center	Eif3l	IDA		Mouse	PMID:11592397
Cellular Component	GO:0016020	membrane	EIF3L	HDA		Human	PMID:19946888
Cellular Component	GO:0005730	nucleolus	Eif3l	IDA		Mouse	PMID:11592397
Cellular Component	GO:0005654	nucleoplasm	Eif3l	IDA		Mouse	PMID:11592397
Cellular Component	GO:0045202	synapse	Eif3l	EXP		Mouse	PMID:25211037
Cellular Component	GO:0045202	synapse	Eif3l	IDA		Mouse	PMID:25211037
Biological Process	GO:0006413	translational initiation	EIF3L	IDA		Human	PMID:17581632
Biological Process	GO:0006413	translational initiation	Eif3l	IDA		Mouse	MGI:MGI:3843422|PMID:17581632
Biological Process	GO:0075525	viral translational termination-reinitiation	EIF3L	IDA		Human	PMID:21347434

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern