Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EIF3C,EIF3CL
  • Mouse genes Eif3c
  • Rat genes Eif3c
  • Zfish genes eif3c
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eif3c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EIF3CL	IPI	UniProtKB:O15372	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EIF3CL	IPI	UniProtKB:O15372	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	EIF3C	IPI	UniProtKB:P60228	Human	PMID:10504338
Molecular Function	GO:0005515	protein binding	EIF3C	IPI	UniProtKB:P60228	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3C	IPI	UniProtKB:Q14152	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3C	IPI	UniProtKB:O00571	Human	PMID:18628297
Molecular Function	GO:0005515	protein binding	EIF3C	IPI	UniProtKB:Q9Q2G4	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	EIF3C	IPI	UniProtKB:O00571	Human	PMID:22323517
Molecular Function	GO:0005515	protein binding	EIF3C	IPI	UniProtKB:P41567	Human	PMID:23623729
Molecular Function	GO:0005515	protein binding	EIF3C	IPI	UniProtKB:P47813	Human	PMID:23623729
Molecular Function	GO:0005515	protein binding	EIF3C	IPI	UniProtKB:P60228	Human	PMID:23623729
Molecular Function	GO:0005515	protein binding	EIF3C	IPI	UniProtKB:Q14152	Human	PMID:23623729
Molecular Function	GO:0005515	protein binding	EIF3C	IPI	UniProtKB:O15371,UniProtKB:P60228,UniProtKB:Q04637	Human	PMID:24092755
Molecular Function	GO:0005515	protein binding	EIF3C	IPI	UniProtKB:P60228	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EIF3C	IPI	UniProtKB:Q05086-2	Human	PMID:29426014
Molecular Function	GO:0005515	protein binding	EIF3C	IPI	UniProtKB:P41567	Human	PMID:29987188
Molecular Function	GO:0005515	protein binding	EIF3C	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Molecular Function	GO:0043022	ribosome binding	EIF3C	IDA		Human	PMID:8995409
Molecular Function	GO:0003723	RNA binding	EIF3C	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	EIF3C	HDA		Human	PMID:22681889
Molecular Function	GO:0003743	translation initiation factor activity	EIF3C	IDA		Human	PMID:17581632
Molecular Function	GO:0003743	translation initiation factor activity	EIF3C	IDA		Human	PMID:25849773
Molecular Function	GO:0003743	translation initiation factor activity	Eif3c	IDA		Mouse	MGI:MGI:3843422|PMID:17581632
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3C	IPI		Human	PMID:17322308
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3C	IDA		Human	PMID:17322308
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3C	IDA		Human	PMID:17581632
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3C	IDA		Human	PMID:18599441
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3C	IDA		Human	PMID:25849773
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	Eif3c	IDA		Mouse	MGI:MGI:3843422|PMID:17581632
Cellular Component	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m	Eif3c	IDA		Mouse	PMID:24003236
Biological Process	GO:1902416	positive regulation of mRNA binding	EIF3C	IPI	UniProtKB:O15371,UniProtKB:P60228,UniProtKB:Q04637	Human	PMID:24092755
Biological Process	GO:0045727	positive regulation of translation	EIF3C	IPI	UniProtKB:O15371,UniProtKB:P60228,UniProtKB:Q04637	Human	PMID:24092755
Biological Process	GO:0006413	translational initiation	EIF3C	IDA		Human	PMID:17581632
Biological Process	GO:0006413	translational initiation	Eif3c	IDA		Mouse	MGI:MGI:3843422|PMID:17581632

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern