Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EFNA3
  • Mouse genes Efna3
  • Rat genes Efna3
  • Zfish genes efna3a,efna3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Efna3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046875	ephrin receptor binding	EFNA3	IPI	UniProtKB:P29320|UniProtKB:Q60750	Human	PMID:11519828
Molecular Function	GO:0046875	ephrin receptor binding	EFNA3	IPI	UniProtKB:Q5JZY3-2	Human	PMID:15777695
Molecular Function	GO:0046875	ephrin receptor binding	EFNA3	IPI	UniProtKB:P29317	Human	PMID:22568954
Molecular Function	GO:0046875	ephrin receptor binding	EFNA3	IPI	UniProtKB:P29319	Human	PMID:22568954
Molecular Function	GO:0046875	ephrin receptor binding	EFNA3	IPI	UniProtKB:P54757	Human	PMID:22568954
Molecular Function	GO:0046875	ephrin receptor binding	EFNA3	IPI	UniProtKB:Q61772	Human	PMID:22568954
Molecular Function	GO:0046875	ephrin receptor binding	Efna3	IPI	UniProtKB:O09127	Mouse	MGI:MGI:85724|PMID:9053851
Molecular Function	GO:0005515	protein binding	EFNA3	IPI	UniProtKB:P50222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EFNA3	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EFNA3	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA3	IPI	UniProtKB:Q5TA81	Human	PMID:32296183
Biological Process	GO:0048013	ephrin receptor signaling pathway	EFNA3	IGI	UniProtKB:P54764	Human	PMID:24217950
Biological Process	GO:0048013	ephrin receptor signaling pathway	Efna3	IDA		Mouse	MGI:MGI:85724|PMID:9053851
Biological Process	GO:0016525	negative regulation of angiogenesis	EFNA3	IDA		Human	PMID:18417479
Biological Process	GO:1902961	positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	EFNA3	IGI	UniProtKB:P54764	Human	PMID:24217950
Biological Process	GO:0045664	regulation of neuron differentiation	Efna3	IDA		Rat	PMID:10954848|RGD:634739

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern