Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EDEM3
  • Mouse genes Edem3
  • Rat genes Edem3
  • Zfish genes edem3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Edem3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	EDEM3	IMP		Human	PMID:25092655
Molecular Function	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	Edem3	IDA		Mouse	PMID:16431915
Cellular Component	GO:0005788	endoplasmic reticulum lumen	Edem3	IDA		Mouse	PMID:16431915
Biological Process	GO:0006516	glycoprotein catabolic process	Edem3	IDA		Mouse	PMID:16431915
Biological Process	GO:1904382	mannose trimming involved in glycoprotein ERAD pathway	EDEM3	IMP		Human	PMID:25092655
Biological Process	GO:1904382	mannose trimming involved in glycoprotein ERAD pathway	Edem3	IDA		Mouse	MGI:MGI:3654428|PMID:16431915
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Edem3	IDA		Mouse	PMID:16431915

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern