Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DYNC2H1
  • Mouse genes Dync2h1
  • Rat genes Dync2h1
  • Zfish genes dync2h1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dync2h1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051959	dynein light intermediate chain binding	Dync2h1	IPI	UniProtKB:Q6AY43	Rat	PMID:12432068|RGD:10047254
Molecular Function	GO:0008569	minus-end-directed microtubule motor activity	DYNC2H1	IDA		Human	PMID:21723285
Molecular Function	GO:0005515	protein binding	DYNC2H1	IPI	UniProtKB:Q8TCX1	Human	PMID:29742051
Cellular Component	GO:0045177	apical part of cell	Dync2h1	IDA		Mouse	MGI:MGI:5009180|PMID:12802074
Cellular Component	GO:0045177	apical part of cell	Dync2h1	IDA		Rat	PMID:8832411|RGD:13207346
Cellular Component	GO:0005930	axoneme	Dync2h1	IDA		Mouse	MGI:MGI:5009180|PMID:12802074
Cellular Component	GO:0005868	cytoplasmic dynein complex	DYNC2H1	IDA		Human	PMID:21723285
Cellular Component	GO:0005868	cytoplasmic dynein complex	DYNC2H1	IDA		Human	PMID:25830415
Cellular Component	GO:0005868	cytoplasmic dynein complex	Dync2h1	IDA		Rat	PMID:9450951|RGD:156431062
Cellular Component	GO:0070062	extracellular exosome	DYNC2H1	HDA		Human	PMID:19056867
Cellular Component	GO:0005794	Golgi apparatus	DYNC2H1	IDA		Human	PMID:8666668
Cellular Component	GO:0005874	microtubule	DYNC2H1	IDA		Human	PMID:21525035
Cellular Component	GO:0031514	motile cilium	Dync2h1	IDA		Mouse	MGI:MGI:5009180|PMID:12802074
Cellular Component	GO:0097730	non-motile cilium	dync2h1	IMP	ZFIN:ZDB-MRPHLNO-100217-23	Zfish	PMID:19474410
Biological Process	GO:0060271	cilium assembly	Dync2h1	IMP	MGI:MGI:3578144	Mouse	PMID:16061793
Biological Process	GO:0060271	cilium assembly	Dync2h1	IMP		Mouse	PMID:16229832
Biological Process	GO:0060271	cilium assembly	Dync2h1	IEP		Rat	PMID:8832411|RGD:13207346
Biological Process	GO:0060271	cilium assembly	dync2h1	IMP	ZFIN:ZDB-GENO-160908-8	Zfish	PMID:27207957
Biological Process	GO:0060976	coronary vasculature development	Dync2h1	IMP		Mouse	PMID:25807483
Biological Process	GO:0007368	determination of left/right symmetry	Dync2h1	IMP		Mouse	PMID:16229832
Biological Process	GO:0007368	determination of left/right symmetry	Dync2h1	IMP	MGI:MGI:3578144	Mouse	PMID:15755804
Biological Process	GO:0007368	determination of left/right symmetry	Dync2h1	IMP	MGI:MGI:3578144	Mouse	PMID:16061793
Biological Process	GO:0007368	determination of left/right symmetry	Dync2h1	IMP		Mouse	PMID:25807483
Biological Process	GO:0009953	dorsal/ventral pattern formation	Dync2h1	IMP		Mouse	PMID:16229832
Biological Process	GO:0009953	dorsal/ventral pattern formation	Dync2h1	IMP	MGI:MGI:3578144	Mouse	PMID:16061793
Biological Process	GO:0009953	dorsal/ventral pattern formation	Dync2h1	IMP	MGI:MGI:3578144	Mouse	PMID:15755804
Biological Process	GO:0009953	dorsal/ventral pattern formation	Dync2h1	IGI	MGI:MGI:95729	Mouse	PMID:21552265
Biological Process	GO:0009953	dorsal/ventral pattern formation	Dync2h1	IGI	MGI:MGI:105373	Mouse	PMID:21552265
Biological Process	GO:0009953	dorsal/ventral pattern formation	Dync2h1	IGI	MGI:MGI:98297	Mouse	PMID:21552265
Biological Process	GO:0030326	embryonic limb morphogenesis	Dync2h1	IMP		Mouse	PMID:16229832
Biological Process	GO:0030900	forebrain development	Dync2h1	IMP		Mouse	PMID:16229832
Biological Process	GO:0007030	Golgi organization	DYNC2H1	IDA		Human	PMID:8666668
Biological Process	GO:0007507	heart development	Dync2h1	IMP		Mouse	PMID:25807483
Biological Process	GO:0035721	intraciliary retrograde transport	Dync2h1	IMP	MGI:MGI:4359237	Mouse	PMID:18488998
Biological Process	GO:0042073	intraciliary transport	dync2h1	IMP	ZFIN:ZDB-MRPHLNO-100217-23	Zfish	PMID:19474410
Biological Process	GO:0001822	kidney development	Dync2h1	IMP	MGI:MGI:5311370	Mouse	PMID:27002738
Biological Process	GO:0030182	neuron differentiation	Dync2h1	IMP	MGI:MGI:3578144	Mouse	PMID:21552265
Biological Process	GO:1905515	non-motile cilium assembly	Dync2h1	IMP	MGI:MGI:4355983	Mouse	PMID:22689656
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	Dync2h1	IMP	MGI:MGI:4359237	Mouse	PMID:18488998
Biological Process	GO:0061512	protein localization to cilium	Dync2h1	IMP		Mouse	PMID:16229832
Biological Process	GO:0016485	protein processing	Dync2h1	IMP	MGI:MGI:3578144	Mouse	PMID:16061793
Biological Process	GO:0016485	protein processing	Dync2h1	IMP		Mouse	PMID:16229832
Biological Process	GO:0021522	spinal cord motor neuron differentiation	Dync2h1	IGI	MGI:MGI:95729	Mouse	PMID:21552265
Biological Process	GO:0021522	spinal cord motor neuron differentiation	Dync2h1	IGI	MGI:MGI:98297	Mouse	PMID:21552265
Biological Process	GO:0021522	spinal cord motor neuron differentiation	Dync2h1	IGI	MGI:MGI:105373	Mouse	PMID:21552265

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern