Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DYNC1I2
  • Mouse genes Dync1i2
  • Rat genes Dync1i2
  • Zfish genes dync1i2a,dync1i2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dync1i2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	DYNC1I2	IPI	UniProtKB:Q9NP97	Human	PMID:24986880
Molecular Function	GO:0005515	protein binding	DYNC1I2	IPI	UniProtKB:Q9NP97	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Dync1i2	IPI	UniProtKB:Q921C5	Mouse	MGI:MGI:5507956|PMID:22956769
Molecular Function	GO:0044877	protein-containing complex binding	Dync1i2	IPI	RGD:62038|RGD:1303182	Rat	PMID:8522607|RGD:728206
Cellular Component	GO:0005813	centrosome	DYNC1I2	IDA		Human	PMID:21399614
Cellular Component	GO:0005737	cytoplasm	Dync1i2	IDA		Rat	PMID:23358504|RGD:12789705
Cellular Component	GO:0030286	dynein complex	DYNC1I2	IPI		Human	PMID:24986880
Cellular Component	GO:0005874	microtubule	DYNC1I2	IDA		Human	PMID:21525035
Cellular Component	GO:0036157	outer dynein arm	Dync1i2	IDA		Mouse	PMID:27353389
Cellular Component	GO:0031982	vesicle	DYNC1I2	IDA		Human	PMID:20682791
Biological Process	GO:0007420	brain development	Dync1i2	IEP		Rat	PMID:8688562|RGD:13207404
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Dync1i2	IEP		Rat	PMID:11536324|RGD:13207410
Biological Process	GO:0007052	mitotic spindle organization	dync1i2a	IMP		Zfish	PMID:31079899
Biological Process	GO:0007052	mitotic spindle organization	dync1i2a	IMP	ZFIN:ZDB-CRISPR-191120-2	Zfish	PMID:31079899
Biological Process	GO:0010977	negative regulation of neuron projection development	Dync1i2	IMP		Rat	PMID:23358504|RGD:12789705

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern