Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DXO
  • Mouse genes Dxo
  • Rat genes Dxo
  • Zfish genes dxo
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dxo

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008409	5'-3' exonuclease activity	Dxo	IDA		Mouse	MGI:MGI:6368050|PMID:30180947
Molecular Function	GO:0008409	5'-3' exonuclease activity	Dxo	IDA		Mouse	MGI:MGI:5488528|PMID:23523372
Molecular Function	GO:0000287	magnesium ion binding	Dxo	IDA		Mouse	MGI:MGI:6368050|PMID:30180947
Molecular Function	GO:0000287	magnesium ion binding	Dxo	IDA		Mouse	MGI:MGI:5488528|PMID:23523372
Molecular Function	GO:0034353	mRNA 5'-diphosphatase activity	Dxo	IDA		Mouse	MGI:MGI:5488528|PMID:23523372
Molecular Function	GO:0003729	mRNA binding	Dxo	IDA		Mouse	MGI:MGI:5488528|PMID:23523372
Molecular Function	GO:0110152	RNA NAD-cap (NAD-forming) hydrolase activity	Dxo	IDA		Mouse	MGI:MGI:6716974|PMID:32374864
Molecular Function	GO:0110152	RNA NAD-cap (NAD-forming) hydrolase activity	Dxo	IDA		Mouse	MGI:MGI:6368104|PMID:28283058
Cellular Component	GO:0005829	cytosol	DXO	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	DXO	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DXO	IDA		Human	PMID:29601584
Cellular Component	GO:0005886	plasma membrane	DXO	IDA		Human	GO_REF:0000052
Biological Process	GO:0006402	mRNA catabolic process	DXO	IDA		Human	PMID:29601584
Biological Process	GO:0006402	mRNA catabolic process	Dxo	IDA		Mouse	MGI:MGI:6368104|PMID:28283058
Biological Process	GO:0006402	mRNA catabolic process	Dxo	IMP		Mouse	MGI:MGI:5488528|PMID:23523372
Biological Process	GO:0110155	NAD-cap decapping	DXO	IDA		Human	PMID:28283058
Biological Process	GO:0110155	NAD-cap decapping	DXO	IDA		Human	PMID:31101919
Biological Process	GO:0110155	NAD-cap decapping	Dxo	IDA		Mouse	MGI:MGI:6716974|PMID:32374864
Biological Process	GO:0110155	NAD-cap decapping	Dxo	IDA		Mouse	MGI:MGI:6368104|PMID:28283058
Biological Process	GO:0071028	nuclear mRNA surveillance	Dxo	IMP		Mouse	MGI:MGI:5488528|PMID:23523372
Biological Process	GO:0090305	nucleic acid phosphodiester bond hydrolysis	Dxo	IDA		Mouse	MGI:MGI:5488528|PMID:23523372
Biological Process	GO:0050779	RNA destabilization	Dxo	IMP		Mouse	MGI:MGI:5488528|PMID:23523372

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern