Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DUSP16
  • Mouse genes Dusp16
  • Rat genes Dusp16
  • Zfish genes dusp16
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dusp16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008432	JUN kinase binding	DUSP16	IPI	UniProtKB:P45983	Human	PMID:11489891
Molecular Function	GO:0051019	mitogen-activated protein kinase binding	DUSP16	IPI	UniProtKB:P28482	Human	PMID:11489891
Molecular Function	GO:0048273	mitogen-activated protein kinase p38 binding	DUSP16	IDA		Human	PMID:11489891
Molecular Function	GO:0016791	phosphatase activity	DUSP16	IDA		Human	PMID:11489891
Molecular Function	GO:0016791	phosphatase activity	DUSP16	IDA		Human	PMID:24531476
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	DUSP16	IMP		Human	PMID:11489891
Molecular Function	GO:0005515	protein binding	DUSP16	IPI	UniProtKB:P45984	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	DUSP16	IPI	UniProtKB:P45983-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DUSP16	IPI	UniProtKB:P45984	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DUSP16	IPI	UniProtKB:P45984	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	DUSP16	IPI	UniProtKB:O76024	Human	PMID:32814053
Cellular Component	GO:0005737	cytoplasm	DUSP16	IDA		Human	PMID:11489891
Cellular Component	GO:0005829	cytosol	Dusp16	IDA		Rat	PMID:23280045|RGD:7775014
Cellular Component	GO:0005654	nucleoplasm	DUSP16	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DUSP16	IDA		Human	PMID:11489891
Cellular Component	GO:0005634	nucleus	Dusp16	IDA		Rat	PMID:23280045|RGD:7775014
Biological Process	GO:0016311	dephosphorylation	DUSP16	IDA		Human	PMID:24531476
Biological Process	GO:0045204	MAPK export from nucleus	DUSP16	IDA		Human	PMID:11489891
Biological Process	GO:0043508	negative regulation of JUN kinase activity	DUSP16	IDA		Human	PMID:11489891
Biological Process	GO:0043409	negative regulation of MAPK cascade	DUSP16	IDA		Human	PMID:11489891
Biological Process	GO:0006470	protein dephosphorylation	DUSP16	IMP		Human	PMID:11489891

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern