Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DRAXIN
  • Mouse genes Draxin
  • Rat genes Draxin
  • Zfish genes draxina,draxinb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Draxin

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	DRAXIN	IPI	UniProtKB:O00634	Human	PMID:26190107
Molecular Function	GO:0005515	protein binding	DRAXIN	IPI	UniProtKB:O95631	Human	PMID:26190107
Molecular Function	GO:0005515	protein binding	Draxin	IPI	UniProtKB:O88572	Mouse	MGI:MGI:4410394|PMID:19857465
Molecular Function	GO:0005515	protein binding	draxina	IPI	UniProtKB:A0A0B5JK74	Zfish	PMID:26190107|ZFIN:ZDB-PUB-150721-6
Molecular Function	GO:0005515	protein binding	draxina	IPI	UniProtKB:A0A0B5JPZ7	Zfish	PMID:26190107|ZFIN:ZDB-PUB-150721-6
Molecular Function	GO:0005515	protein binding	draxina	IPI	UniProtKB:A0A0B5JQ66	Zfish	PMID:26190107|ZFIN:ZDB-PUB-150721-6
Cellular Component	GO:0005576	extracellular region	Draxin	IDA		Mouse	PMID:20621059
Biological Process	GO:0021960	anterior commissure morphogenesis	Draxin	IMP		Mouse	MGI:MGI:5467661|PMID:23206892
Biological Process	GO:0007411	axon guidance	Draxin	IMP		Mouse	MGI:MGI:3832346|PMID:19150847
Biological Process	GO:0007417	central nervous system development	draxina	IMP	ZFIN:ZDB-MRPHLNO-120410-2	Zfish	PMID:22265871
Biological Process	GO:0021528	commissural neuron differentiation in spinal cord	Draxin	IMP		Mouse	MGI:MGI:3832346|PMID:19150847
Biological Process	GO:0021516	dorsal spinal cord development	Draxin	IMP		Mouse	MGI:MGI:3832346|PMID:19150847
Biological Process	GO:0030900	forebrain development	Draxin	IMP		Mouse	MGI:MGI:3832346|PMID:19150847
Biological Process	GO:0110088	hippocampal neuron apoptotic process	Draxin	IMP	MGI:MGI:3833678	Mouse	PMID:19808066
Biological Process	GO:0030517	negative regulation of axon extension	Draxin	IDA		Mouse	PMID:20621059
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Draxin	IDA		Mouse	MGI:MGI:4410394|PMID:19857465
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	draxina	IMP	ZFIN:ZDB-MRPHLNO-120410-2	Zfish	PMID:22265871
Biological Process	GO:0110091	negative regulation of hippocampal neuron apoptotic process	Draxin	IMP	MGI:MGI:3833678	Mouse	PMID:19808066
Biological Process	GO:0010977	negative regulation of neuron projection development	Draxin	IMP		Mouse	MGI:MGI:5467661|PMID:23206892
Biological Process	GO:0051402	neuron apoptotic process	Draxin	IMP	MGI:MGI:3833678	Mouse	PMID:19808066
Biological Process	GO:0030182	neuron differentiation	draxina	IMP	ZFIN:ZDB-MRPHLNO-120410-2	Zfish	PMID:22265871

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern