Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DNASE1
  • Mouse genes Dnase1
  • Rat genes Dnase1
  • Zfish genes dnase1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dnase1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004530	deoxyribonuclease I activity	Dnase1	IMP		Mouse	MGI:MGI:3687616|PMID:15015938
Molecular Function	GO:0004530	deoxyribonuclease I activity	Dnase1	IDA		Rat	PMID:12005024|RGD:1298888
Molecular Function	GO:0004536	DNA nuclease activity	Dnase1	IDA		Rat	PMID:8428592|RGD:10047160
Molecular Function	GO:0005515	protein binding	DNASE1	IPI	UniProtKB:P68133	Human	PMID:12849983
Cellular Component	GO:0070062	extracellular exosome	DNASE1	HDA		Human	PMID:23533145
Biological Process	GO:0006308	DNA catabolic process	Dnase1	IDA		Mouse	MGI:MGI:6094744|PMID:29191910
Biological Process	GO:0002283	neutrophil activation involved in immune response	Dnase1	IDA		Mouse	MGI:MGI:6094744|PMID:29191910
Biological Process	GO:0002673	regulation of acute inflammatory response	Dnase1	IDA		Mouse	MGI:MGI:6094744|PMID:29191910
Biological Process	GO:0070948	regulation of neutrophil mediated cytotoxicity	Dnase1	IDA		Mouse	MGI:MGI:6094744|PMID:29191910

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern