Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DNAJB8
  • Mouse genes Dnajb8
  • Rat genes Dnajb8
  • Zfish genes dnajb6a,dnajb6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dnajb8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0044183	protein folding chaperone	DNAJB8	IDA		Human	PMID:23612975
Molecular Function	GO:0051087	protein-folding chaperone binding	DNAJB8	IPI	UniProtKB:P0DMV8	Human	PMID:21231916
Molecular Function	GO:0051087	protein-folding chaperone binding	DNAJB8	IPI	UniProtKB:P0DMV9	Human	PMID:21231916
Molecular Function	GO:0051087	protein-folding chaperone binding	DNAJB8	IPI	UniProtKB:P17066	Human	PMID:21231916
Molecular Function	GO:0051082	unfolded protein binding	DNAJB8	IDA		Human	PMID:21231916
Cellular Component	GO:0005829	cytosol	DNAJB8	IDA		Human	PMID:21231916
Cellular Component	GO:0005635	nuclear envelope	dnajb6b	IDA		Zfish	PMID:27642634
Cellular Component	GO:0005634	nucleus	DNAJB8	IDA		Human	PMID:21231916
Cellular Component	GO:0005634	nucleus	DNAJB8	HDA		Human	PMID:21630459
Biological Process	GO:0061077	chaperone-mediated protein folding	DNAJB8	IDA		Human	PMID:23612975
Biological Process	GO:0007626	locomotory behavior	dnajb6b	IMP	ZFIN:ZDB-MRPHLNO-140722-5	Zfish	PMID:25866181
Biological Process	GO:0007626	locomotory behavior	dnajb6a	IMP	ZFIN:ZDB-MRPHLNO-150622-2	Zfish	PMID:25866181
Biological Process	GO:0016203	muscle attachment	dnajb6b	IMP	ZFIN:ZDB-MRPHLNO-140722-5	Zfish	PMID:22366786
Biological Process	GO:0030239	myofibril assembly	dnajb6b	IMP	ZFIN:ZDB-MRPHLNO-140722-5	Zfish	PMID:25866181
Biological Process	GO:0090084	negative regulation of inclusion body assembly	DNAJB8	IDA		Human	PMID:21231916
Biological Process	GO:1903573	negative regulation of response to endoplasmic reticulum stress	dnajb6b	IMP		Zfish	PMID:27642634
Biological Process	GO:0007519	skeletal muscle tissue development	dnajb6b	IMP	ZFIN:ZDB-MRPHLNO-140722-5	Zfish	PMID:25866181
Biological Process	GO:0007519	skeletal muscle tissue development	dnajb6a	IMP	ZFIN:ZDB-MRPHLNO-150622-2	Zfish	PMID:25866181

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern